Hemispheric specialization for emotional expression: A reexamination of results from intracarotid administration of sodium amobarbital

Gregory P. Lee; David W. Loring; Kimford J. Meader; Betty B. Brooks

doi:10.1016/0278-2626(90)90019-K

Hemispheric specialization for emotional expression: A reexamination of results from intracarotid administration of sodium amobarbital

Gregory P. Lee, David W. Loring, Kimford J. Meader, Betty B. Brooks

Occupational Therapy

Research output: Contribution to journal › Article › peer-review

61 Scopus citations

Abstract

Emotional and behavioral responses to sodium amobarbital injection were examined in 44 epilepsy surgery candidates. Thirty-three emotional reactions occurred in 26 patients, 44% of the reactions following right hemisphere injection and 32% after injection of the left hemisphere. Among all patients examined, laughter/elated mood was statistically more frequent following right hemisphere injection while crying was statistically associated with left hemisphere injections. These observed effects were not related to amobarbital dose, sex, bilateral hemispheric inactivation (angiographic crossflow), general cognitive status, or side of seizure onset. These results support differing specialization of emotional expression in the right and left cerebral hemispheres and their subcortical connections.

Original language	English (US)
Pages (from-to)	267-280
Number of pages	14
Journal	Brain and Cognition
Volume	12
Issue number	2
DOIs	https://doi.org/10.1016/0278-2626(90)90019-K
State	Published - Mar 1990

ASJC Scopus subject areas

Neuropsychology and Physiological Psychology
Experimental and Cognitive Psychology
Developmental and Educational Psychology
Arts and Humanities (miscellaneous)
Cognitive Neuroscience

Access to Document

10.1016/0278-2626(90)90019-K

Cite this

@article{1b1cd99d935a4baf9ebe7afb032bba11,

title = "Hemispheric specialization for emotional expression: A reexamination of results from intracarotid administration of sodium amobarbital",

abstract = "Emotional and behavioral responses to sodium amobarbital injection were examined in 44 epilepsy surgery candidates. Thirty-three emotional reactions occurred in 26 patients, 44% of the reactions following right hemisphere injection and 32% after injection of the left hemisphere. Among all patients examined, laughter/elated mood was statistically more frequent following right hemisphere injection while crying was statistically associated with left hemisphere injections. These observed effects were not related to amobarbital dose, sex, bilateral hemispheric inactivation (angiographic crossflow), general cognitive status, or side of seizure onset. These results support differing specialization of emotional expression in the right and left cerebral hemispheres and their subcortical connections.",

author = "Lee, {Gregory P.} and Loring, {David W.} and Meader, {Kimford J.} and Brooks, {Betty B.}",

note = "Funding Information: This work was supported, in part, by the Medical College of Georgia Research Institute Grants program and NIH/NIA Clinical Investigator Award No. 1 KO8 AGOO314. We thank Elaine Thompson for her help in data collection. Address correspondence and reprint requests to Gregory P. Lee, Ph.D., Section of Neurosurgery, Medical College of Georgia, Augusta, GA 30912-4010.",

year = "1990",

month = mar,

doi = "10.1016/0278-2626(90)90019-K",

language = "English (US)",

volume = "12",

pages = "267--280",

journal = "Brain and Cognition",

issn = "0278-2626",

publisher = "Academic Press Inc.",

number = "2",

}

TY - JOUR

T1 - Hemispheric specialization for emotional expression

T2 - A reexamination of results from intracarotid administration of sodium amobarbital

AU - Lee, Gregory P.

AU - Loring, David W.

AU - Meader, Kimford J.

AU - Brooks, Betty B.

N1 - Funding Information: This work was supported, in part, by the Medical College of Georgia Research Institute Grants program and NIH/NIA Clinical Investigator Award No. 1 KO8 AGOO314. We thank Elaine Thompson for her help in data collection. Address correspondence and reprint requests to Gregory P. Lee, Ph.D., Section of Neurosurgery, Medical College of Georgia, Augusta, GA 30912-4010.

PY - 1990/3

Y1 - 1990/3

N2 - Emotional and behavioral responses to sodium amobarbital injection were examined in 44 epilepsy surgery candidates. Thirty-three emotional reactions occurred in 26 patients, 44% of the reactions following right hemisphere injection and 32% after injection of the left hemisphere. Among all patients examined, laughter/elated mood was statistically more frequent following right hemisphere injection while crying was statistically associated with left hemisphere injections. These observed effects were not related to amobarbital dose, sex, bilateral hemispheric inactivation (angiographic crossflow), general cognitive status, or side of seizure onset. These results support differing specialization of emotional expression in the right and left cerebral hemispheres and their subcortical connections.

AB - Emotional and behavioral responses to sodium amobarbital injection were examined in 44 epilepsy surgery candidates. Thirty-three emotional reactions occurred in 26 patients, 44% of the reactions following right hemisphere injection and 32% after injection of the left hemisphere. Among all patients examined, laughter/elated mood was statistically more frequent following right hemisphere injection while crying was statistically associated with left hemisphere injections. These observed effects were not related to amobarbital dose, sex, bilateral hemispheric inactivation (angiographic crossflow), general cognitive status, or side of seizure onset. These results support differing specialization of emotional expression in the right and left cerebral hemispheres and their subcortical connections.

UR - http://www.scopus.com/inward/record.url?scp=0025393126&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0025393126&partnerID=8YFLogxK

U2 - 10.1016/0278-2626(90)90019-K

DO - 10.1016/0278-2626(90)90019-K

M3 - Article

C2 - 2340155

AN - SCOPUS:0025393126

SN - 0278-2626

VL - 12

SP - 267

EP - 280

JO - Brain and Cognition

JF - Brain and Cognition

IS - 2

ER -

Hemispheric specialization for emotional expression: A reexamination of results from intracarotid administration of sodium amobarbital

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this