How viruses evade host responses

Neema Agrawal, Hasan Korkaya, Shahid Jameel

Research output: Contribution to journalReview article

3 Scopus citations

Abstract

Humans have evolved a highly complex defence system to combat a wide variety of pathogens. Among the pathogens, developing a remedy for most of the viral infections still remains a great challenge as viruses evolve very rapidly as well as produce a variety of proteins. These features provide viruses with strategies to evade almost any hurdle imposed by the host defences to block their replication. It is important to understand the mechanisms of virus-host interactions, as this information can prove useful in symptomatic treatment of viral infections and aid in the design of antiviral vaccines. Further, since viruses rely almost entirely on the host cell machinery for their propagation, these studies educate us about our own cells and the basic mechanisms of gene expression and immunity.

Original languageEnglish (US)
Pages (from-to)711-724
Number of pages14
JournalCurrent Science
Volume79
Issue number6
StatePublished - Sep 25 2000
Externally publishedYes

ASJC Scopus subject areas

  • General

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  • Cite this

    Agrawal, N., Korkaya, H., & Jameel, S. (2000). How viruses evade host responses. Current Science, 79(6), 711-724.