Hypertension induced morphological and physiological changes in cells of the arterial wall

Patricia Martinez-Quinones, Cameron G. McCarthy, Stephanie W. Watts, Nicole S. Klee, Amel Komic, Fabiano B. Calmasini, Fernanda Priviero, Alexander Warner, Yu Chenghao, Camilla F. Wenceslau

Research output: Contribution to journalReview article

3 Citations (Scopus)

Abstract

Morphological and physiological changes in the vasculature have been described in the evolution and maintenance of hypertension. Hypertension-induced vascular dysfunction may present itself as a contributing, or consequential factor, to vascular remodeling caused by chronically elevated systemic arterial blood pressure. Changes in all vessel layers, from the endothelium to the perivascular adipose tissue (PVAT), have been described. This mini-review focuses on the current knowledge of the structure and function of the vessel layers, specifically muscular arteries: intima, media, adventitia, PVAT, and the cell types harbored within each vessel layer. The contributions of each cell type to vessel homeostasis and pathophysiological development of hypertension will be highlighted.

Original languageEnglish (US)
Pages (from-to)1067-1078
Number of pages12
JournalAmerican journal of hypertension
Volume31
Issue number10
DOIs
StatePublished - Sep 11 2018

Fingerprint

Cell Wall
Hypertension
Adipose Tissue
Adventitia
Endothelium
Blood Vessels
Arterial Pressure
Homeostasis
Arteries
Maintenance
Vascular Remodeling

Keywords

  • blood pressure; cell types
  • hypertension
  • vascular
  • vessel wall

ASJC Scopus subject areas

  • Internal Medicine

Cite this

Martinez-Quinones, P., McCarthy, C. G., Watts, S. W., Klee, N. S., Komic, A., Calmasini, F. B., ... Wenceslau, C. F. (2018). Hypertension induced morphological and physiological changes in cells of the arterial wall. American journal of hypertension, 31(10), 1067-1078. https://doi.org/10.1093/ajh/hpy083

Hypertension induced morphological and physiological changes in cells of the arterial wall. / Martinez-Quinones, Patricia; McCarthy, Cameron G.; Watts, Stephanie W.; Klee, Nicole S.; Komic, Amel; Calmasini, Fabiano B.; Priviero, Fernanda; Warner, Alexander; Chenghao, Yu; Wenceslau, Camilla F.

In: American journal of hypertension, Vol. 31, No. 10, 11.09.2018, p. 1067-1078.

Research output: Contribution to journalReview article

Martinez-Quinones, P, McCarthy, CG, Watts, SW, Klee, NS, Komic, A, Calmasini, FB, Priviero, F, Warner, A, Chenghao, Y & Wenceslau, CF 2018, 'Hypertension induced morphological and physiological changes in cells of the arterial wall', American journal of hypertension, vol. 31, no. 10, pp. 1067-1078. https://doi.org/10.1093/ajh/hpy083
Martinez-Quinones P, McCarthy CG, Watts SW, Klee NS, Komic A, Calmasini FB et al. Hypertension induced morphological and physiological changes in cells of the arterial wall. American journal of hypertension. 2018 Sep 11;31(10):1067-1078. https://doi.org/10.1093/ajh/hpy083
Martinez-Quinones, Patricia ; McCarthy, Cameron G. ; Watts, Stephanie W. ; Klee, Nicole S. ; Komic, Amel ; Calmasini, Fabiano B. ; Priviero, Fernanda ; Warner, Alexander ; Chenghao, Yu ; Wenceslau, Camilla F. / Hypertension induced morphological and physiological changes in cells of the arterial wall. In: American journal of hypertension. 2018 ; Vol. 31, No. 10. pp. 1067-1078.
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