TY - JOUR
T1 - Implications of left bundle branch block in patient treatment
AU - Kumar, Vineet
AU - Venkataraman, Rajesh
AU - Aljaroudi, Wael
AU - Osorio, Jose
AU - Heo, Jaekyeong
AU - Iskandrian, Ami E.
AU - Hage, Fadi G.
PY - 2013/1/15
Y1 - 2013/1/15
N2 - Left bundle branch block (LBBB) causes an abnormal pattern of cardiac activation and affects regional myocardial function. Although recognition of LBBB on the surface electrocardiogram is straightforward, dissecting its effect on patient treatment and outcome can be more challenging. The altered pattern of cardiac activation in LBBB causes electrical and mechanical ventricular dyssynchrony, influences ischemia detection on the surface electrocardiogram, and affects stress testing and imaging modalities dependent on wall motion and thickening. Restoration of synchrony by biventricular pacing can improve symptoms and longevity in carefully selected patients. The diagnostic, prognostic, and therapeutic implications of LBBB across this spectrum are discussed in this review.
AB - Left bundle branch block (LBBB) causes an abnormal pattern of cardiac activation and affects regional myocardial function. Although recognition of LBBB on the surface electrocardiogram is straightforward, dissecting its effect on patient treatment and outcome can be more challenging. The altered pattern of cardiac activation in LBBB causes electrical and mechanical ventricular dyssynchrony, influences ischemia detection on the surface electrocardiogram, and affects stress testing and imaging modalities dependent on wall motion and thickening. Restoration of synchrony by biventricular pacing can improve symptoms and longevity in carefully selected patients. The diagnostic, prognostic, and therapeutic implications of LBBB across this spectrum are discussed in this review.
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U2 - 10.1016/j.amjcard.2012.09.029
DO - 10.1016/j.amjcard.2012.09.029
M3 - Review article
C2 - 23111137
AN - SCOPUS:84872048482
SN - 0002-9149
VL - 111
SP - 291
EP - 300
JO - American Journal of Cardiology
JF - American Journal of Cardiology
IS - 2
ER -