The phenomena of neuron-to-electrode surface attachment NESA) via self-assembly of alkanethiol was investigated. The phenomena of hysteresis indicated cysteamine (CA) self-assembly monolayers (SAM) displays greater amphiphilic character than 11-amino-1-undecanethiol (11-AUT)-SAM. The tapping mode atomic force microscopy (AFM) also confirmed 6% increase and 22% decrease in surface roughness when compared to clean, unmodified and sputter-deposited gold. The results show that covalent immobilization of adhesion-promoting proteins enhanced NESA by tightly anchoring cells to electrode.
ASJC Scopus subject areas
- Physical and Theoretical Chemistry
- Colloid and Surface Chemistry