Improving neuron-to-electrode Surface attachment via alkanethiol self-assembly: An alternating current impedance study

Gymama E. Slaughter, Erhard Bieberich, Gary E. Wnek, Kenneth J. Wynne, Anthony Guiseppi-Elie

Research output: Contribution to journalArticle

39 Citations (Scopus)

Abstract

The phenomena of neuron-to-electrode surface attachment NESA) via self-assembly of alkanethiol was investigated. The phenomena of hysteresis indicated cysteamine (CA) self-assembly monolayers (SAM) displays greater amphiphilic character than 11-amino-1-undecanethiol (11-AUT)-SAM. The tapping mode atomic force microscopy (AFM) also confirmed 6% increase and 22% decrease in surface roughness when compared to clean, unmodified and sputter-deposited gold. The results show that covalent immobilization of adhesion-promoting proteins enhanced NESA by tightly anchoring cells to electrode.

Original languageEnglish (US)
Pages (from-to)7189-7200
Number of pages12
JournalLangmuir
Volume20
Issue number17
DOIs
StatePublished - Aug 17 2004

Fingerprint

neurons
Self assembly
Neurons
attachment
self assembly
alternating current
impedance
Electrodes
electrodes
Monolayers
cysteamine
Cysteamine
immobilization
Gold
Hysteresis
Atomic force microscopy
surface roughness
adhesion
Adhesion
Surface roughness

ASJC Scopus subject areas

  • Physical and Theoretical Chemistry
  • Colloid and Surface Chemistry

Cite this

Slaughter, G. E., Bieberich, E., Wnek, G. E., Wynne, K. J., & Guiseppi-Elie, A. (2004). Improving neuron-to-electrode Surface attachment via alkanethiol self-assembly: An alternating current impedance study. Langmuir, 20(17), 7189-7200. https://doi.org/10.1021/la049192s

Improving neuron-to-electrode Surface attachment via alkanethiol self-assembly : An alternating current impedance study. / Slaughter, Gymama E.; Bieberich, Erhard; Wnek, Gary E.; Wynne, Kenneth J.; Guiseppi-Elie, Anthony.

In: Langmuir, Vol. 20, No. 17, 17.08.2004, p. 7189-7200.

Research output: Contribution to journalArticle

Slaughter, GE, Bieberich, E, Wnek, GE, Wynne, KJ & Guiseppi-Elie, A 2004, 'Improving neuron-to-electrode Surface attachment via alkanethiol self-assembly: An alternating current impedance study', Langmuir, vol. 20, no. 17, pp. 7189-7200. https://doi.org/10.1021/la049192s
Slaughter, Gymama E. ; Bieberich, Erhard ; Wnek, Gary E. ; Wynne, Kenneth J. ; Guiseppi-Elie, Anthony. / Improving neuron-to-electrode Surface attachment via alkanethiol self-assembly : An alternating current impedance study. In: Langmuir. 2004 ; Vol. 20, No. 17. pp. 7189-7200.
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