In vitro activity of a new pneumocandin antifungal, L-743,872, against azole-susceptible and -resistant Candida species

Jose Antonio Vazquez, Maria Lynch, Dina Boikov, Jack D. Sobel

Research output: Contribution to journalArticle

106 Citations (Scopus)

Abstract

The in vitro activity of a new pneumocandin, L-743,872, was evaluated with 108 strains of Candida and compared with the activities of various antifungals. L-743,872 demonstrated the best activity against azole- susceptible and -resistant strains of C. albicans, C. glabrata, C. tropicalis, C. parapsilosis, and C. kefyr and less activity against C. krusei, C. lusitaniae, and C. guilliermondii.

Original languageEnglish (US)
Pages (from-to)1612-1614
Number of pages3
JournalAntimicrobial Agents and Chemotherapy
Volume41
Issue number7
StatePublished - Jul 1 1997
Externally publishedYes

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caspofungin
Azoles
Candida
In Vitro Techniques

ASJC Scopus subject areas

  • Pharmacology (medical)

Cite this

In vitro activity of a new pneumocandin antifungal, L-743,872, against azole-susceptible and -resistant Candida species. / Vazquez, Jose Antonio; Lynch, Maria; Boikov, Dina; Sobel, Jack D.

In: Antimicrobial Agents and Chemotherapy, Vol. 41, No. 7, 01.07.1997, p. 1612-1614.

Research output: Contribution to journalArticle

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