In vivo endocrine studies in adrenal rest tumor of ovary

Charles R. Parker, Edouard Servy, Paul G. McDonough, Virendra B. Mahesh

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Radioimmunoassay of several plasma steroids and gonadotropins and routine urinary steroid analyses were performed on a patient before during and after removal of an ovarian adrenal rest tumor. Follicle-stimulating hormone and luteinizing hormone were low but testosterone, 5α-dihydrotestosterone, progesterone, 17α OH-progesterone, and Δ4-androstenedione were markedly elevated prior to surgery. Urinary 17 ketosteroids were slightly elevated and did not decrease during treatment with dexa methasone although urinary 17 hydroxycortico-steroids, plasma cortisol, and plasma dehydro-epiandrosterone did suppress. The elevated plasma steroids were significantly lowered after tumor excision, and the patient, once amcnor rhelc, now has normal, ovulatory menstrual cycles.

Original languageEnglish (US)
Pages (from-to)327-332
Number of pages6
JournalObstetrics and Gynecology
Volume44
Issue number3
StatePublished - Jan 1 1974

Fingerprint

Adrenal Rest Tumor
Ovary
Steroids
Progesterone
Androsterone
17-Ketosteroids
Androstenedione
Dihydrotestosterone
Follicle Stimulating Hormone
Menstrual Cycle
Luteinizing Hormone
Gonadotropins
Radioimmunoassay
Hydrocortisone
Testosterone
Neoplasms

ASJC Scopus subject areas

  • Obstetrics and Gynecology

Cite this

Parker, C. R., Servy, E., McDonough, P. G., & Mahesh, V. B. (1974). In vivo endocrine studies in adrenal rest tumor of ovary. Obstetrics and Gynecology, 44(3), 327-332.

In vivo endocrine studies in adrenal rest tumor of ovary. / Parker, Charles R.; Servy, Edouard; McDonough, Paul G.; Mahesh, Virendra B.

In: Obstetrics and Gynecology, Vol. 44, No. 3, 01.01.1974, p. 327-332.

Research output: Contribution to journalArticle

Parker, CR, Servy, E, McDonough, PG & Mahesh, VB 1974, 'In vivo endocrine studies in adrenal rest tumor of ovary', Obstetrics and Gynecology, vol. 44, no. 3, pp. 327-332.
Parker CR, Servy E, McDonough PG, Mahesh VB. In vivo endocrine studies in adrenal rest tumor of ovary. Obstetrics and Gynecology. 1974 Jan 1;44(3):327-332.
Parker, Charles R. ; Servy, Edouard ; McDonough, Paul G. ; Mahesh, Virendra B. / In vivo endocrine studies in adrenal rest tumor of ovary. In: Obstetrics and Gynecology. 1974 ; Vol. 44, No. 3. pp. 327-332.
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