In vivo endocrine studies in adrenal rest tumor of ovary

Charles R. Parker, Edouard Servy, Paul G. McDonough, Virendra B. Mahesh

Research output: Contribution to journalArticlepeer-review

8 Scopus citations


Radioimmunoassay of several plasma steroids and gonadotropins and routine urinary steroid analyses were performed on a patient before during and after removal of an ovarian adrenal rest tumor. Follicle-stimulating hormone and luteinizing hormone were low but testosterone, 5α-dihydrotestosterone, progesterone, 17α OH-progesterone, and Δ4-androstenedione were markedly elevated prior to surgery. Urinary 17 ketosteroids were slightly elevated and did not decrease during treatment with dexa methasone although urinary 17 hydroxycortico-steroids, plasma cortisol, and plasma dehydro-epiandrosterone did suppress. The elevated plasma steroids were significantly lowered after tumor excision, and the patient, once amcnor rhelc, now has normal, ovulatory menstrual cycles.

Original languageEnglish (US)
Pages (from-to)327-332
Number of pages6
JournalObstetrics and gynecology
Issue number3
StatePublished - Sep 1974
Externally publishedYes

ASJC Scopus subject areas

  • Obstetrics and Gynecology


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