Intrafibrillar collagen mineralization produced by biomimetic hierarchical nanoapatite assembly

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Abstract

Phosphorous-based templating analogs of extracellular matrix proteins are used as templates in conjunction with polycarboxylic acid-stabilized amorphous calcium phosphate nanoprecursors to create a highly ordered intrafibrillar apatite crystallite assembly within a collagen fibril. The assembly recapitulates the gap and overlap arrangement of collagen molecules.

Original languageEnglish (US)
Pages (from-to)975-980
Number of pages6
JournalAdvanced Materials
Volume23
Issue number8
DOIs
Publication statusPublished - Feb 22 2011

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Keywords

  • biomimetics
  • biomineralization
  • collagen
  • templating

ASJC Scopus subject areas

  • Materials Science(all)
  • Mechanics of Materials
  • Mechanical Engineering

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