Intrafibrillar collagen mineralization produced by biomimetic hierarchical nanoapatite assembly

Yan Liu, Nan Li, Yi Pin Qi, Lin Dai, Thomas E. Bryan, Jing Mao, David Henry Pashley, Franklin Chi Meng Tay

Research output: Contribution to journalArticlepeer-review

105 Scopus citations

Abstract

Phosphorous-based templating analogs of extracellular matrix proteins are used as templates in conjunction with polycarboxylic acid-stabilized amorphous calcium phosphate nanoprecursors to create a highly ordered intrafibrillar apatite crystallite assembly within a collagen fibril. The assembly recapitulates the gap and overlap arrangement of collagen molecules.

Original languageEnglish (US)
Pages (from-to)975-980
Number of pages6
JournalAdvanced Materials
Volume23
Issue number8
DOIs
StatePublished - Feb 22 2011

Keywords

  • biomimetics
  • biomineralization
  • collagen
  • templating

ASJC Scopus subject areas

  • Materials Science(all)
  • Mechanics of Materials
  • Mechanical Engineering

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