Ischemic colitis: A forgotten entity. Results of a retrospective study in 118 patients

Muhammed Sherid, Humberto Sifuentes, Salih Samo, Samian Sulaiman, Husein Husein, Ruth Tupper, Sankara N. Sethuraman, Charles Spurr, John A. Vainder, Subbaramiah Sridhar

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12 Scopus citations

Abstract

Objective: The aim of our study was to document our 6-year experiences in identifing the clinical characteristics, laboratory findings, risk factors and the outcomes of patients with ischemic colitis (IC) in a community hospital setting. Methods: The medical records of patients who were diagnosed with IC from 2007 to 2013 in two community hospitals were retrospectively reviewed. Their clinical characteristics, laboratory results, radiological, endoscopic and histological evidence, anatomic location of the lesion, comorbidities, concomitant use of drugs, and so on, were collected. Results: A total of 118 patients with IC was identified, most were elderly individuals with a female predominance. The most common symptoms were abdominal pain, rectal bleeding and diarrhea. Hypertension, hyperlipidemia, coronary artery disease and diabetes mellitus were the most common comorbidities. Erythema, edema and erosions/ulcerations were the most common endoscopic findings. Left colon was the most affected location of lesion (84.8%), and there was one case of pancolitis. The descending colon was the most common affected segment, while rectum was the least affected segment. Severe IC occurred in 12.7% of the patients. Death within 30 days from the diagnosis of the disease occurred in 4.2%. Conclusions: IC is majorly occurred in elderly with a female predominance. Cardiovascular disease and its assoicated risk factors are the most common comorbidities. Left colon is the most affected location of the disease and the overall mortality rate was 4.2%. Physicians should make every effort to identify these patients, especially those with high risks.

Original languageEnglish (US)
Pages (from-to)606-613
Number of pages8
JournalJournal of Digestive Diseases
Volume15
Issue number11
DOIs
Publication statusPublished - Nov 1 2014

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Keywords

  • Colitis
  • Colonoscopy
  • Computed tomography
  • Histology
  • Ischemic colitis

ASJC Scopus subject areas

  • Gastroenterology

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