It's the Bloody Gallbladder! Spontaneous Gallbladder Hemorrhage Following Factor Xa Inhibition

Mohammad Umair Azam, Muaz A. Ibrahim, Isaac Perry, Steven B. Ellison, Amanda Barrett, Kenneth J Vega

Research output: Contribution to journalArticlepeer-review

Abstract

Spontaneous gallbladder hemorrhage (SGBH) is a rare diagnosis related to trauma, malignancy or vascular abnormalities, associated with significant morbidity and mortality. We present a case of SGBH in a 55-year-old patient with right upper quadrant (RUQ) pain following initiation of apixaban for deep vein thrombosis post recent kidney transplant. Multiple imaging studies revealed a distended gallbladder with heterogeneous hyperdense material in the lumen and cystic duct obstruction. Surgery revealed a gallbladder with chronic cholecystitis, hemorrhage and hematoma. This case highlights a rare adverse event of anticoagulation, and SGBH should be considered when acute RUQ pain occurs in this setting.

Original languageEnglish (US)
JournalJournal of the National Medical Association
DOIs
StateAccepted/In press - 2021

Keywords

  • Anticoagulation
  • Gallbladder
  • Hemorrhage

ASJC Scopus subject areas

  • Medicine(all)

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