TY - JOUR
T1 - Lichen planus, lichenoid drug reactions, and lichenoid mucositis
AU - Derossi, Scott S.
AU - Ciarrocca, Katharine N.
N1 - Copyright:
Copyright 2018 Elsevier B.V., All rights reserved.
PY - 2005/1
Y1 - 2005/1
N2 - OLP and lichenoid reaction are a relatively common oral mucosal disease process encountered in clinical practice. This mucocutaneous disease can manifest as desquamative gingivitis, asymptomatic Wickham's striae or plaques, or severe, painful erosions or ulcerations anywhere in the oral cavity. Although the exact agent initiating LP is unknown, current research points to a number of complex immunologic events and cells that are responsible for the inflammatory destruction and chronicity of these lesions. Currently, the mainstay of treatment remains topical corticosteroids, but newer therapies such a tacrolimus are available for recalcitrant lesions. In cases of lichenoid mucositis or reactions, treatment should always be directed toward identifying and removing the presumed causative agent. Given the apparent risk of squamous cell carcinoma in these patients, frequent follow-up and repeat biopsy when indicated are vital.
AB - OLP and lichenoid reaction are a relatively common oral mucosal disease process encountered in clinical practice. This mucocutaneous disease can manifest as desquamative gingivitis, asymptomatic Wickham's striae or plaques, or severe, painful erosions or ulcerations anywhere in the oral cavity. Although the exact agent initiating LP is unknown, current research points to a number of complex immunologic events and cells that are responsible for the inflammatory destruction and chronicity of these lesions. Currently, the mainstay of treatment remains topical corticosteroids, but newer therapies such a tacrolimus are available for recalcitrant lesions. In cases of lichenoid mucositis or reactions, treatment should always be directed toward identifying and removing the presumed causative agent. Given the apparent risk of squamous cell carcinoma in these patients, frequent follow-up and repeat biopsy when indicated are vital.
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U2 - 10.1016/j.cden.2004.08.004
DO - 10.1016/j.cden.2004.08.004
M3 - Review article
C2 - 15567362
AN - SCOPUS:9444222474
SN - 0011-8532
VL - 49
SP - 77
EP - 89
JO - Dental clinics of North America
JF - Dental clinics of North America
IS - 1 SPEC.ISS.
ER -