Light microscopic and scanning electron microscopic retrieval analyses of implanted biomaterials retrieved from humans and experimental animals.

D. E. Steflik, Raymond S Corpe, Timothy R Young, Gregory R Parr, M. Tucker, M. Sims, J. Tinley, A. Sisk, M. McDaniel

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

This paper reports analysis obtained from 200 implant cases retrieved from humans and submitted to the American Academy of Implant Dentistry Research Foundation, Medical College of Georgia implant retrieval center. The samples that were not decalcified were embedded in polymethylmethacrylate and examined with scanning electron microscopy and routine light, polarized, or Nomarski microscopy. Cases included both orthopedic and dental implants, as well as entire mandibles and portions of maxillae obtained at autopsy. A significant number of submitted implants had substantial amounts of adhered bone, which permitted evaluation of human bone remodeling to osseointegrated implants. These implants failed because of implant fracture. As was observed with animal studies, healthy bone supported these implants, with the bone containing an interdigitating canaliculi network that provided communication between interfacial osteocytes and osteocytes deeper within the remodeled osteonal and trabecular bone. Early dental implants containing a coating of beads showed a connective tissue interface, which corresponded to the bead surface of specific orthopedic implants that underwent some degree of micromovement. This is in contrast with the excellent response reported for successful contemporary beaded implants. Significant numbers of osseointegrated fractured hydroxyapatite (HA)-coated dental implants demonstrated the adequate serviceability of these implants before biomaterial fracture. In contrast, the HA coating was dissociated from retrieved orthopedic implants, leading to extensive cup loosening and case failure. This study, therefore, underscores the need for evaluation of failed human dental and orthopedic implants. Correlations can be drawn between human retrieval and experimental animal studies.

Original languageEnglish (US)
Pages (from-to)5-15
Number of pages11
JournalThe Journal of oral implantology
Volume27
Issue number1
DOIs
StatePublished - Jan 1 2001

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Dental Implants
Biocompatible Materials
Orthopedics
Electrons
Light
Osteocytes
Durapatite
Bone and Bones
Bone Remodeling
Maxilla
Polymethyl Methacrylate
Dentistry
Mandible
Connective Tissue
Electron Scanning Microscopy
Biomedical Research
Microscopy
Autopsy
Communication

ASJC Scopus subject areas

  • Oral Surgery

Cite this

Light microscopic and scanning electron microscopic retrieval analyses of implanted biomaterials retrieved from humans and experimental animals. / Steflik, D. E.; Corpe, Raymond S; Young, Timothy R; Parr, Gregory R; Tucker, M.; Sims, M.; Tinley, J.; Sisk, A.; McDaniel, M.

In: The Journal of oral implantology, Vol. 27, No. 1, 01.01.2001, p. 5-15.

Research output: Contribution to journalArticle

Steflik, D. E. ; Corpe, Raymond S ; Young, Timothy R ; Parr, Gregory R ; Tucker, M. ; Sims, M. ; Tinley, J. ; Sisk, A. ; McDaniel, M. / Light microscopic and scanning electron microscopic retrieval analyses of implanted biomaterials retrieved from humans and experimental animals. In: The Journal of oral implantology. 2001 ; Vol. 27, No. 1. pp. 5-15.
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