Linkage of a gene for dominant non-syndromic deafness to chromosome 19

Hung Chih Chen, Li Ni, Kunihiro Fukushima, Jacquie Marietta, Marsha O'neill, Paul Coucke, Patrick Willems, Richard J.H. Smith

Research output: Contribution to journalArticle

64 Citations (Scopus)

Abstract

Inherited hearing impairment can occur either in the presence of other clinical features (syndromic hearing loss, SHL) or in isolation (non-syndromic hearing loss, NSHL). The latter is more common and is highly heterogeneous. To date, six NSHL loci have been mapped. We report the identification of a seventh locus (DFNA4) on chromosome 19q13 and suggest DM kinase as a possible candidate gene.

Original languageEnglish (US)
Pages (from-to)1073-1076
Number of pages4
JournalHuman Molecular Genetics
Volume4
Issue number6
DOIs
StatePublished - Jun 1 1995

Fingerprint

Chromosomes, Human, Pair 19
Dominant Genes
Deafness
Hearing Loss
Chromosomes
Genes

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics
  • Genetics(clinical)

Cite this

Chen, H. C., Ni, L., Fukushima, K., Marietta, J., O'neill, M., Coucke, P., ... Smith, R. J. H. (1995). Linkage of a gene for dominant non-syndromic deafness to chromosome 19. Human Molecular Genetics, 4(6), 1073-1076. https://doi.org/10.1093/hmg/4.6.1073

Linkage of a gene for dominant non-syndromic deafness to chromosome 19. / Chen, Hung Chih; Ni, Li; Fukushima, Kunihiro; Marietta, Jacquie; O'neill, Marsha; Coucke, Paul; Willems, Patrick; Smith, Richard J.H.

In: Human Molecular Genetics, Vol. 4, No. 6, 01.06.1995, p. 1073-1076.

Research output: Contribution to journalArticle

Chen, HC, Ni, L, Fukushima, K, Marietta, J, O'neill, M, Coucke, P, Willems, P & Smith, RJH 1995, 'Linkage of a gene for dominant non-syndromic deafness to chromosome 19', Human Molecular Genetics, vol. 4, no. 6, pp. 1073-1076. https://doi.org/10.1093/hmg/4.6.1073
Chen HC, Ni L, Fukushima K, Marietta J, O'neill M, Coucke P et al. Linkage of a gene for dominant non-syndromic deafness to chromosome 19. Human Molecular Genetics. 1995 Jun 1;4(6):1073-1076. https://doi.org/10.1093/hmg/4.6.1073
Chen, Hung Chih ; Ni, Li ; Fukushima, Kunihiro ; Marietta, Jacquie ; O'neill, Marsha ; Coucke, Paul ; Willems, Patrick ; Smith, Richard J.H. / Linkage of a gene for dominant non-syndromic deafness to chromosome 19. In: Human Molecular Genetics. 1995 ; Vol. 4, No. 6. pp. 1073-1076.
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