Linkage of a gene for dominant non-syndromic deafness to chromosome 19

Achih H. Chen, Li Ni, Kunihiro Fukushima, Jacquie Marietta, Marsha O'neill, Paul Coucke, Patrick Willems, Richard J.H. Smith

Research output: Contribution to journalArticle

66 Scopus citations

Abstract

Inherited hearing impairment can occur either in the presence of other clinical features (syndromic hearing loss, SHL) or in isolation (non-syndromic hearing loss, NSHL). The latter is more common and is highly heterogeneous. To date, six NSHL loci have been mapped. We report the identification of a seventh locus (DFNA4) on chromosome 19q13 and suggest DM kinase as a possible candidate gene.

Original languageEnglish (US)
Pages (from-to)1073-1076
Number of pages4
JournalHuman Molecular Genetics
Volume4
Issue number6
DOIs
StatePublished - Jun 1 1995

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics
  • Genetics(clinical)

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    Chen, A. H., Ni, L., Fukushima, K., Marietta, J., O'neill, M., Coucke, P., Willems, P., & Smith, R. J. H. (1995). Linkage of a gene for dominant non-syndromic deafness to chromosome 19. Human Molecular Genetics, 4(6), 1073-1076. https://doi.org/10.1093/hmg/4.6.1073