Mechanism of endothelin-1 activation of map kinases in neonatal pulmonary vascular smooth muscle

Medicine & Life Sciences

• Endothelin-1 100%
• Mitogen-Activated Protein Kinases 91%
• Vascular Smooth Muscle 90%
• Protein Kinase C 72%
• Phosphotransferases 71%
• 2-(1-(3-dimethylaminopropyl)-5-methoxyindol-3-yl)-3-(1H-indol-3-yl)maleimide 53%
• Lung 49%
• cyclo(Trp-Asp-Pro-Val-Leu) 44%
• Phosphorylation 42%
• Cell Proliferation 40%
• Protein C Inhibitor 36%
• Mitogen-Activated Protein Kinase 1 34%
• Protein Kinase Inhibitors 32%
• Isoenzymes 30%
• rottlerin 23%
• BQ 788 23%
• diphenyleneiodonium 22%
• 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one 18%
• Mitogen-Activated Protein Kinase 3 17%
• Protein-Serine-Threonine Kinases 17%
• Second Messenger Systems 16%
• Vasoconstrictor Agents 16%
• Mitogen-Activated Protein Kinase Kinases 16%
• Smooth Muscle Myocytes 13%
• Intercellular Signaling Peptides and Proteins 12%
• Reactive Oxygen Species 12%
• Western Blotting 10%
• Blood Vessels 9%