Membrane glycolipids in stem cells

Robert K. Yu, Yusuke Suzuki, Makoto Yanagisawa

Research output: Contribution to journalReview article

31 Scopus citations

Abstract

Stem cells, such as embryonic stem cells, hematopoietic stem cells, neural stem cells, mesenchymal stem cells, and very small embryonic-like stem cells, are undifferentiated cells that are endowed with a high potential for proliferation and the capacity for self-renewal with retention of pluri/multipotency to differentiate into their progenies. Recently, studies regarding the biological functions of glycolipids and cell surface microdomains (caveolae, lipid rafts, or glycolipid-enriched microdomains) in stem cells are emerging. In this review, we introduce the expression patterns of glycolipids and the functional roles of cell surface microdomains in stem cells.

Original languageEnglish (US)
Pages (from-to)1694-1699
Number of pages6
JournalFEBS Letters
Volume584
Issue number9
DOIs
Publication statusPublished - May 1 2010

    Fingerprint

Keywords

  • Cancer stem cell
  • Cell surface microdomain
  • Embryonic stem cell
  • Glycolipid
  • Hematopoietic stem cell
  • Mesenchymal stem cell
  • Neural stem cell

ASJC Scopus subject areas

  • Biophysics
  • Structural Biology
  • Biochemistry
  • Molecular Biology
  • Genetics
  • Cell Biology

Cite this