Microfibrous borate bioactive glass dressing sequesters bone-bound bisphosphonate in the presence of simulated body fluid

Chandrani Pramanik, Tianda Wang, Sushanta Ghoshal, Lina Niu, Bradley A. Newcomb, Yaodong Liu, Carolyn M. Primus, Hailan Feng, David H. Pashley, Satish Kumar, Franklin R. Tay

Research output: Contribution to journalArticle

3 Scopus citations

Abstract

Ion exchange occurs between borate bioactive glass and simulated body fluid. Borate bioactive glass dressings may be used for managing bisphosphonate-related osteonecrosis of the jaw through the formation of a complex incorporating leached calcium and borate ions and sequestered bone-bound bisphosphonates.

Original languageEnglish (US)
Pages (from-to)959-963
Number of pages5
JournalJournal of Materials Chemistry B
Volume3
Issue number6
DOIs
StatePublished - Feb 14 2015

ASJC Scopus subject areas

  • Chemistry(all)
  • Biomedical Engineering
  • Materials Science(all)

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    Pramanik, C., Wang, T., Ghoshal, S., Niu, L., Newcomb, B. A., Liu, Y., Primus, C. M., Feng, H., Pashley, D. H., Kumar, S., & Tay, F. R. (2015). Microfibrous borate bioactive glass dressing sequesters bone-bound bisphosphonate in the presence of simulated body fluid. Journal of Materials Chemistry B, 3(6), 959-963. https://doi.org/10.1039/c4tb02035a