Microporous, Demineralized Collagen Matrices in Intact Radicular Dentin Created by Commonly Used Calcium-depleting Endodontic Irrigants

Franklin Chi Meng Tay, James L. Gutmann, David Henry Pashley

Research output: Contribution to journalArticle

35 Citations (Scopus)

Abstract

The use of calcium-depleting solutions in restorative dentistry results in demineralization of intact coronal dentin beneath smear layers. Likewise, application of calcium-depleting irrigants as final rinses might create demineralized collagen matrices in intact radicular dentin after removal of root canal wall smear layers created during canal shaping. These unsupported collagen matrices collapse on desiccation and might be difficult to detect in scanning electron microscopy dehydration techniques traditionally used in endodontic research. Demineralized collagen matrices were identified, by using a hexamethyldisilazane dehydration protocol, on the surface of smear layer-depleted radicular dentin when NaOCl was used as initial rinse, followed by the use of 17% ethylenediaminetetraacetic acid or BioPure MTAD as the final rinse. Compaction of conventional root filling materials over a demineralized collagen matrix in instrumented dentin is analogous to performing the same procedure against the predentin collagen network in the uninstrumented parts of root canals. The potential consequences of this process are, however, unknown.

Original languageEnglish (US)
Pages (from-to)1086-1090
Number of pages5
JournalJournal of Endodontics
Volume33
Issue number9
DOIs
StatePublished - Sep 1 2007

Fingerprint

Endodontics
Dentin
Smear Layer
Collagen
Calcium
Dental Pulp Cavity
Dehydration
Desiccation
Dentistry
Edetic Acid
Electron Scanning Microscopy
Research

Keywords

  • Collapse
  • EDTA
  • MTAD
  • NaOCl
  • demineralized dentin matrix

ASJC Scopus subject areas

  • Dentistry(all)

Cite this

Microporous, Demineralized Collagen Matrices in Intact Radicular Dentin Created by Commonly Used Calcium-depleting Endodontic Irrigants. / Tay, Franklin Chi Meng; Gutmann, James L.; Pashley, David Henry.

In: Journal of Endodontics, Vol. 33, No. 9, 01.09.2007, p. 1086-1090.

Research output: Contribution to journalArticle

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