Mitochondrial fission and fusion

Research output: Contribution to journalArticle

37 Citations (Scopus)

Abstract

Mitochondrial fission and fusion have been recognized as critical processes in the health of mitochondria and cells. Two decades of studies have generated a great deal of information about mitochondrial fission and fusion; however, still much needs to be understood for the basic molecular mechanisms of these important cellular processes. The core protein factors for mitochondrial fission and fusion are dynamin proteins that possess membrane-remodeling properties. This short review covers a recent development and understanding of the mechanisms by which these mechanochemical enzymes mediate mitochondrial fission and fusion.

Original languageEnglish (US)
Pages (from-to)1725-1735
Number of pages11
JournalBiochemical Society Transactions
Volume44
Issue number6
DOIs
StatePublished - Dec 15 2016

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Mitochondrial Dynamics
Fusion reactions
Dynamins
Mitochondria
Membrane Proteins
Proteins
Health
Membranes
Enzymes

ASJC Scopus subject areas

  • Biochemistry

Cite this

Mitochondrial fission and fusion. / Lee, Hakjoo; Yoon, Yisang.

In: Biochemical Society Transactions, Vol. 44, No. 6, 15.12.2016, p. 1725-1735.

Research output: Contribution to journalArticle

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