Molecular control of nitric oxide synthases in the cardiovascular system

Andreas Papapetropoulos, Radu Daniel Rudic, William C. Sessa

Research output: Contribution to journalReview article

161 Scopus citations

Abstract

Nitric oxide plays an important role in cardiovascular homeostasis. In this review, the regulation of the three nitric oxide synthase isoforms in the cardiovascular system are examined at molecular and cellular levels. In addition, recent information gleaned from the use of NOS knockout mice are discussed.

Original languageEnglish (US)
Pages (from-to)509-520
Number of pages12
JournalCardiovascular Research
Volume43
Issue number3
DOIs
StatePublished - Aug 15 1999
Externally publishedYes

Keywords

  • Cardiovascular system
  • Molecular control
  • Nitric oxide synthases

ASJC Scopus subject areas

  • Physiology
  • Cardiology and Cardiovascular Medicine
  • Physiology (medical)

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