Monitoring for Extra-Intestinal Cancers in IBD

Research output: Contribution to journalReview article

9 Citations (Scopus)

Abstract

Multiple studies have demonstrated an increased risk for extra-intestinal cancers in inflammatory bowel disease (IBD) patients, mainly from treatment modalities. Prominent cancers that are related to IBD treatment include the following: lymphoproliferative disorders associated with thiopurine use, hepatosplenic T cell lymphoma primarily in younger male patients on thiopurines and anti-tumor necrosis factor (TNF) agents, non-melanoma skin cancers in patients treated with thiopurines and anti-TNF agents, and melanomas in patients who are on monotherapy with anti-TNF agents. In addition, women with IBD may have higher rates of cervical dysplasia and cervical cancer. The focus of this review is to provide a comprehensive overview on extra-intestinal cancers in IBD patients and how to monitor for these malignancies.

Original languageEnglish (US)
Article number42
JournalCurrent Gastroenterology Reports
Volume17
Issue number11
DOIs
StatePublished - Nov 22 2015

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Intestinal Neoplasms
Inflammatory Bowel Diseases
Tumor Necrosis Factor-alpha
Uterine Cervical Dysplasia
Lymphoproliferative Disorders
T-Cell Lymphoma
Skin Neoplasms
Uterine Cervical Neoplasms
Melanoma
Neoplasms
Therapeutics

Keywords

  • Cervical cancer
  • Cervical dysplasia
  • Crohn’s disease
  • Extra-intestinal cancers
  • Hepatosplenic T cell lymphoma
  • Inflammatory bowel disease
  • Lymphoma
  • Lymphoproliferative disorders
  • Melanoma
  • Non-Hodgkin lymphoma
  • Non-melanoma skin cancer
  • Ulcerative colitis

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Monitoring for Extra-Intestinal Cancers in IBD. / Sifuentes, Humberto; Kane, S.

In: Current Gastroenterology Reports, Vol. 17, No. 11, 42, 22.11.2015.

Research output: Contribution to journalReview article

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