TY - JOUR
T1 - More than Just a Hole in the Wall
T2 - Evolving Management and Treatment Paradigms of Suppurative Gastritis
AU - Coles, Michael
AU - Madray, Victoria
AU - Cox, Kayla
AU - Uy, Pearl
AU - Sharma, Amol
N1 - Publisher Copyright:
© 2020, This is a U.S. Government work and not under copyright protection in the US; foreign copyright protection may apply.
PY - 2020/8/1
Y1 - 2020/8/1
N2 - Suppurative gastritis is an uncommon lesion and often an occult cause of upper abdominal pain without florid signs of a septic focus. There are two main phenotypic forms: (1) localized, also referred to as gastric abscess; and (2) diffuse, in which the differential diagnosis includes a more diverse range of benign and malignant lesions. Cross-section imaging such as CT allows for rapid diagnosis and demonstrates the location and extent, but not the specific etiology, of the lesion. High-frequency endoscopic ultrasound (EUS) and fine needle aspiration (FNA) have greatly improved the safety and diagnostic accuracy of suppurative gastritis. EUS/FNA provides an opportunity to arbitrate among infectious and malignant or benign tumors, to identify specific pathogens, and in cases of localized gastric abscesses, for resolution by decompression. More advanced endoscopic procedures are rapidly emerging to supplement EUS/FNA, which already demonstrate the promise of improved, minimally-invasive diagnosis and effective management for the diverse range of lesions causing suppurative gastritis.
AB - Suppurative gastritis is an uncommon lesion and often an occult cause of upper abdominal pain without florid signs of a septic focus. There are two main phenotypic forms: (1) localized, also referred to as gastric abscess; and (2) diffuse, in which the differential diagnosis includes a more diverse range of benign and malignant lesions. Cross-section imaging such as CT allows for rapid diagnosis and demonstrates the location and extent, but not the specific etiology, of the lesion. High-frequency endoscopic ultrasound (EUS) and fine needle aspiration (FNA) have greatly improved the safety and diagnostic accuracy of suppurative gastritis. EUS/FNA provides an opportunity to arbitrate among infectious and malignant or benign tumors, to identify specific pathogens, and in cases of localized gastric abscesses, for resolution by decompression. More advanced endoscopic procedures are rapidly emerging to supplement EUS/FNA, which already demonstrate the promise of improved, minimally-invasive diagnosis and effective management for the diverse range of lesions causing suppurative gastritis.
KW - Abdominal pain
KW - Endoscopic ultrasound (EUS)/fine needle aspiration (FNA)
KW - Gastric wall abscess
KW - Suppurative gastritis
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U2 - 10.1007/s10620-020-06356-6
DO - 10.1007/s10620-020-06356-6
M3 - Review article
C2 - 32533540
AN - SCOPUS:85086323968
SN - 0163-2116
VL - 65
SP - 2203
EP - 2209
JO - Digestive Diseases and Sciences
JF - Digestive Diseases and Sciences
IS - 8
ER -