Near-Drowning Complicated by Brain Abscess due to Petriellidium boydii

John F. Fisher, Smith Shadomy, J. Robert Teabeaut, Janet Woodward, Gene E. Michaels, Mark A. Newman, Elizabeth White, Paul Cook, Annette Seagraves, Farivar Yaghmai, J. Peter Rissing

Research output: Contribution to journalArticle

49 Citations (Scopus)

Abstract

Extracutaneous infection from Petriellidium boydii is an unusual occurrence despite the ubiquity of the organism in nature. Central nervous system infection by this organism is extremely rare, only seven previous reports having been found. The rarity of this manifestation prompted the report of a brain abscess occurring in a previously healthy youth after a near-drowning. The source of the infection was likely to have been the river water at the accident site, from which P boydii was isolated. Although previous in vitro susceptibility data and failure of amphotericin B therapy in a similar infection suggested miconazole treatment might be beneficial, the organism causing the brain abscess was resistant to miconazole and amphotericin B. This report emphasizes the urgent need for safer and more predictably effective alternatives to currently available antifungal agents.

Original languageEnglish (US)
Pages (from-to)511-513
Number of pages3
JournalArchives of Neurology
Volume39
Issue number8
DOIs
StatePublished - Aug 1982

Fingerprint

Pseudallescheria
Near Drowning
Brain Abscess
Miconazole
Amphotericin B
Infection
Central Nervous System Infections
Antifungal Agents
Rivers
Accidents
Water
Therapeutics
Drowning
Organism

ASJC Scopus subject areas

  • Arts and Humanities (miscellaneous)
  • Clinical Neurology

Cite this

Near-Drowning Complicated by Brain Abscess due to Petriellidium boydii. / Fisher, John F.; Shadomy, Smith; Teabeaut, J. Robert; Woodward, Janet; Michaels, Gene E.; Newman, Mark A.; White, Elizabeth; Cook, Paul; Seagraves, Annette; Yaghmai, Farivar; Rissing, J. Peter.

In: Archives of Neurology, Vol. 39, No. 8, 08.1982, p. 511-513.

Research output: Contribution to journalArticle

Fisher, JF, Shadomy, S, Teabeaut, JR, Woodward, J, Michaels, GE, Newman, MA, White, E, Cook, P, Seagraves, A, Yaghmai, F & Rissing, JP 1982, 'Near-Drowning Complicated by Brain Abscess due to Petriellidium boydii', Archives of Neurology, vol. 39, no. 8, pp. 511-513. https://doi.org/10.1001/archneur.1982.00510200053011
Fisher, John F. ; Shadomy, Smith ; Teabeaut, J. Robert ; Woodward, Janet ; Michaels, Gene E. ; Newman, Mark A. ; White, Elizabeth ; Cook, Paul ; Seagraves, Annette ; Yaghmai, Farivar ; Rissing, J. Peter. / Near-Drowning Complicated by Brain Abscess due to Petriellidium boydii. In: Archives of Neurology. 1982 ; Vol. 39, No. 8. pp. 511-513.
@article{ed6722e420e74a1eab7a90e6338d06e7,
title = "Near-Drowning Complicated by Brain Abscess due to Petriellidium boydii",
abstract = "Extracutaneous infection from Petriellidium boydii is an unusual occurrence despite the ubiquity of the organism in nature. Central nervous system infection by this organism is extremely rare, only seven previous reports having been found. The rarity of this manifestation prompted the report of a brain abscess occurring in a previously healthy youth after a near-drowning. The source of the infection was likely to have been the river water at the accident site, from which P boydii was isolated. Although previous in vitro susceptibility data and failure of amphotericin B therapy in a similar infection suggested miconazole treatment might be beneficial, the organism causing the brain abscess was resistant to miconazole and amphotericin B. This report emphasizes the urgent need for safer and more predictably effective alternatives to currently available antifungal agents.",
author = "Fisher, {John F.} and Smith Shadomy and Teabeaut, {J. Robert} and Janet Woodward and Michaels, {Gene E.} and Newman, {Mark A.} and Elizabeth White and Paul Cook and Annette Seagraves and Farivar Yaghmai and Rissing, {J. Peter}",
year = "1982",
month = "8",
doi = "10.1001/archneur.1982.00510200053011",
language = "English (US)",
volume = "39",
pages = "511--513",
journal = "Archives of Neurology",
issn = "0003-9942",
publisher = "American Medical Association",
number = "8",

}

TY - JOUR

T1 - Near-Drowning Complicated by Brain Abscess due to Petriellidium boydii

AU - Fisher, John F.

AU - Shadomy, Smith

AU - Teabeaut, J. Robert

AU - Woodward, Janet

AU - Michaels, Gene E.

AU - Newman, Mark A.

AU - White, Elizabeth

AU - Cook, Paul

AU - Seagraves, Annette

AU - Yaghmai, Farivar

AU - Rissing, J. Peter

PY - 1982/8

Y1 - 1982/8

N2 - Extracutaneous infection from Petriellidium boydii is an unusual occurrence despite the ubiquity of the organism in nature. Central nervous system infection by this organism is extremely rare, only seven previous reports having been found. The rarity of this manifestation prompted the report of a brain abscess occurring in a previously healthy youth after a near-drowning. The source of the infection was likely to have been the river water at the accident site, from which P boydii was isolated. Although previous in vitro susceptibility data and failure of amphotericin B therapy in a similar infection suggested miconazole treatment might be beneficial, the organism causing the brain abscess was resistant to miconazole and amphotericin B. This report emphasizes the urgent need for safer and more predictably effective alternatives to currently available antifungal agents.

AB - Extracutaneous infection from Petriellidium boydii is an unusual occurrence despite the ubiquity of the organism in nature. Central nervous system infection by this organism is extremely rare, only seven previous reports having been found. The rarity of this manifestation prompted the report of a brain abscess occurring in a previously healthy youth after a near-drowning. The source of the infection was likely to have been the river water at the accident site, from which P boydii was isolated. Although previous in vitro susceptibility data and failure of amphotericin B therapy in a similar infection suggested miconazole treatment might be beneficial, the organism causing the brain abscess was resistant to miconazole and amphotericin B. This report emphasizes the urgent need for safer and more predictably effective alternatives to currently available antifungal agents.

UR - http://www.scopus.com/inward/record.url?scp=0019944934&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0019944934&partnerID=8YFLogxK

U2 - 10.1001/archneur.1982.00510200053011

DO - 10.1001/archneur.1982.00510200053011

M3 - Article

C2 - 7103801

AN - SCOPUS:0019944934

VL - 39

SP - 511

EP - 513

JO - Archives of Neurology

JF - Archives of Neurology

SN - 0003-9942

IS - 8

ER -