Neuropathy and IgM paraproteinemia: Differential binding of IgM M-proteins to peripheral nerve glycolipids

S. Kusunoki; T. Kohriyama; A. R. Pachner; N. Latov; R. K. Yu

doi:10.1212/wnl.37.11.1795

Neuropathy and IgM paraproteinemia: Differential binding of IgM M-proteins to peripheral nerve glycolipids

S. Kusunoki, T. Kohriyama, A. R. Pachner, N. Latov, R. K. Yu

Research output: Contribution to journal › Article › peer-review

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Abstract

Two patients with neuropathy and IgM paraproteinemia displayed different immunoreactivity to acidic peripheral nerve glycolipids: In one patient, immunostaining on thin-layer chromatographic plate revealed binding of the IgM to sulfated glucuronosyl paragloboside (SGPG) and sulfated glucuronosyl lactosaminyl paragloboside (SGLPG). The other IgM bound SGPG, SGLPG, and a new third glycolipid. Immunoreactivity of the IgM varies in this syndrome.

Original language	English (US)
Pages (from-to)	1795-1797
Number of pages	3
Journal	Neurology
Volume	37
Issue number	11
DOIs	https://doi.org/10.1212/wnl.37.11.1795
State	Published - Nov 1987
Externally published	Yes

ASJC Scopus subject areas

Clinical Neurology

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abstract = "Two patients with neuropathy and IgM paraproteinemia displayed different immunoreactivity to acidic peripheral nerve glycolipids: In one patient, immunostaining on thin-layer chromatographic plate revealed binding of the IgM to sulfated glucuronosyl paragloboside (SGPG) and sulfated glucuronosyl lactosaminyl paragloboside (SGLPG). The other IgM bound SGPG, SGLPG, and a new third glycolipid. Immunoreactivity of the IgM varies in this syndrome.",

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AU - Kohriyama, T.

AU - Pachner, A. R.

AU - Latov, N.

AU - Yu, R. K.

PY - 1987/11

Y1 - 1987/11

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AB - Two patients with neuropathy and IgM paraproteinemia displayed different immunoreactivity to acidic peripheral nerve glycolipids: In one patient, immunostaining on thin-layer chromatographic plate revealed binding of the IgM to sulfated glucuronosyl paragloboside (SGPG) and sulfated glucuronosyl lactosaminyl paragloboside (SGLPG). The other IgM bound SGPG, SGLPG, and a new third glycolipid. Immunoreactivity of the IgM varies in this syndrome.

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Neuropathy and IgM paraproteinemia: Differential binding of IgM M-proteins to peripheral nerve glycolipids

Abstract

ASJC Scopus subject areas

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