Neuropathy and IgM paraproteinemia: Differential binding of IgM M-proteins to peripheral nerve glycolipids

S. Kusunoki, T. Kohriyama, A. R. Pachner, N. Latov, Robert K Yu

Research output: Contribution to journalArticle

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Abstract

Two patients with neuropathy and IgM paraproteinemia displayed different immunoreactivity to acidic peripheral nerve glycolipids: In one patient, immunostaining on thin-layer chromatographic plate revealed binding of the IgM to sulfated glucuronosyl paragloboside (SGPG) and sulfated glucuronosyl lactosaminyl paragloboside (SGLPG). The other IgM bound SGPG, SGLPG, and a new third glycolipid. Immunoreactivity of the IgM varies in this syndrome.

Original languageEnglish (US)
Pages (from-to)1795-1797
Number of pages3
JournalNeurology
Volume37
Issue number11
StatePublished - Jan 1 1987
Externally publishedYes

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Paraproteinemias
Glycolipids
Peripheral Nerves
Immunoglobulin M
paragloboside
immunoglobulin-binding factors

ASJC Scopus subject areas

  • Clinical Neurology

Cite this

Kusunoki, S., Kohriyama, T., Pachner, A. R., Latov, N., & Yu, R. K. (1987). Neuropathy and IgM paraproteinemia: Differential binding of IgM M-proteins to peripheral nerve glycolipids. Neurology, 37(11), 1795-1797.

Neuropathy and IgM paraproteinemia : Differential binding of IgM M-proteins to peripheral nerve glycolipids. / Kusunoki, S.; Kohriyama, T.; Pachner, A. R.; Latov, N.; Yu, Robert K.

In: Neurology, Vol. 37, No. 11, 01.01.1987, p. 1795-1797.

Research output: Contribution to journalArticle

Kusunoki, S, Kohriyama, T, Pachner, AR, Latov, N & Yu, RK 1987, 'Neuropathy and IgM paraproteinemia: Differential binding of IgM M-proteins to peripheral nerve glycolipids', Neurology, vol. 37, no. 11, pp. 1795-1797.
Kusunoki, S. ; Kohriyama, T. ; Pachner, A. R. ; Latov, N. ; Yu, Robert K. / Neuropathy and IgM paraproteinemia : Differential binding of IgM M-proteins to peripheral nerve glycolipids. In: Neurology. 1987 ; Vol. 37, No. 11. pp. 1795-1797.
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