Normal values for pharyngeal pH monitoring

Neil N. Chheda, Melanie W. Seybt, Robert R. Schade, Gregory N Postma

Research output: Contribution to journalArticle

34 Citations (Scopus)

Abstract

Objectives: We performed a prospective study of asymptomatic adult volunteers to establish normative values of pharyngeal pH using a novel pH probe. Methods: The Dx-pH probe is a novel pH device capable of measuring liquid and aerosolized acid levels. Twenty asymptomatic patients (Reflux Symptom Index less than 10 and Reflux Finding Score less than 6) underwent simultaneous investigation with this probe placed in the oropharynx and a dual antimony probe placed in the hypopharynx and esophagus. The reflux parameters measured from the oropharyngeal probe included the percentage of time and the number of events in which the pH was less than 5.5, 5.0, 4.5, and 4.0. Results: The upper limits of normal (95th percentile) for the number of events below pH of 5.5, 5.0, 4.5, and 4.0 per 24-hour period were 16.6, 10.7, 7.4, and 0.2, respectively. The upper limits of normal (95th percentile) for an acid exposure time below pH of 5.5, 5.0, 4.5, and 4.0 per 24-hour period were 820 seconds, 385 seconds, 75 seconds, and 3 seconds, respectively. Conclusions: Normative pharyngeal pH values are presented. Further studies are required to determine clinical relevance.

Original languageEnglish (US)
Pages (from-to)166-171
Number of pages6
JournalAnnals of Otology, Rhinology and Laryngology
Volume118
Issue number3
DOIs
StatePublished - Jan 1 2009

Fingerprint

Reference Values
Antimony
Hypopharynx
Oropharynx
Acids
Esophagus
Volunteers
Prospective Studies
Equipment and Supplies

Keywords

  • Extraesophageal reflux
  • Laryngopharyngeal reflux
  • PH monitor

ASJC Scopus subject areas

  • Otorhinolaryngology

Cite this

Normal values for pharyngeal pH monitoring. / Chheda, Neil N.; Seybt, Melanie W.; Schade, Robert R.; Postma, Gregory N.

In: Annals of Otology, Rhinology and Laryngology, Vol. 118, No. 3, 01.01.2009, p. 166-171.

Research output: Contribution to journalArticle

Chheda, Neil N. ; Seybt, Melanie W. ; Schade, Robert R. ; Postma, Gregory N. / Normal values for pharyngeal pH monitoring. In: Annals of Otology, Rhinology and Laryngology. 2009 ; Vol. 118, No. 3. pp. 166-171.
@article{bc37f6429190421a91e9bc690d85ffc5,
title = "Normal values for pharyngeal pH monitoring",
abstract = "Objectives: We performed a prospective study of asymptomatic adult volunteers to establish normative values of pharyngeal pH using a novel pH probe. Methods: The Dx-pH probe is a novel pH device capable of measuring liquid and aerosolized acid levels. Twenty asymptomatic patients (Reflux Symptom Index less than 10 and Reflux Finding Score less than 6) underwent simultaneous investigation with this probe placed in the oropharynx and a dual antimony probe placed in the hypopharynx and esophagus. The reflux parameters measured from the oropharyngeal probe included the percentage of time and the number of events in which the pH was less than 5.5, 5.0, 4.5, and 4.0. Results: The upper limits of normal (95th percentile) for the number of events below pH of 5.5, 5.0, 4.5, and 4.0 per 24-hour period were 16.6, 10.7, 7.4, and 0.2, respectively. The upper limits of normal (95th percentile) for an acid exposure time below pH of 5.5, 5.0, 4.5, and 4.0 per 24-hour period were 820 seconds, 385 seconds, 75 seconds, and 3 seconds, respectively. Conclusions: Normative pharyngeal pH values are presented. Further studies are required to determine clinical relevance.",
keywords = "Extraesophageal reflux, Laryngopharyngeal reflux, PH monitor",
author = "Chheda, {Neil N.} and Seybt, {Melanie W.} and Schade, {Robert R.} and Postma, {Gregory N}",
year = "2009",
month = "1",
day = "1",
doi = "10.1177/000348940911800302",
language = "English (US)",
volume = "118",
pages = "166--171",
journal = "Annals of Otology, Rhinology and Laryngology",
issn = "0003-4894",
publisher = "Annals Publishing Company",
number = "3",

}

TY - JOUR

T1 - Normal values for pharyngeal pH monitoring

AU - Chheda, Neil N.

AU - Seybt, Melanie W.

AU - Schade, Robert R.

AU - Postma, Gregory N

PY - 2009/1/1

Y1 - 2009/1/1

N2 - Objectives: We performed a prospective study of asymptomatic adult volunteers to establish normative values of pharyngeal pH using a novel pH probe. Methods: The Dx-pH probe is a novel pH device capable of measuring liquid and aerosolized acid levels. Twenty asymptomatic patients (Reflux Symptom Index less than 10 and Reflux Finding Score less than 6) underwent simultaneous investigation with this probe placed in the oropharynx and a dual antimony probe placed in the hypopharynx and esophagus. The reflux parameters measured from the oropharyngeal probe included the percentage of time and the number of events in which the pH was less than 5.5, 5.0, 4.5, and 4.0. Results: The upper limits of normal (95th percentile) for the number of events below pH of 5.5, 5.0, 4.5, and 4.0 per 24-hour period were 16.6, 10.7, 7.4, and 0.2, respectively. The upper limits of normal (95th percentile) for an acid exposure time below pH of 5.5, 5.0, 4.5, and 4.0 per 24-hour period were 820 seconds, 385 seconds, 75 seconds, and 3 seconds, respectively. Conclusions: Normative pharyngeal pH values are presented. Further studies are required to determine clinical relevance.

AB - Objectives: We performed a prospective study of asymptomatic adult volunteers to establish normative values of pharyngeal pH using a novel pH probe. Methods: The Dx-pH probe is a novel pH device capable of measuring liquid and aerosolized acid levels. Twenty asymptomatic patients (Reflux Symptom Index less than 10 and Reflux Finding Score less than 6) underwent simultaneous investigation with this probe placed in the oropharynx and a dual antimony probe placed in the hypopharynx and esophagus. The reflux parameters measured from the oropharyngeal probe included the percentage of time and the number of events in which the pH was less than 5.5, 5.0, 4.5, and 4.0. Results: The upper limits of normal (95th percentile) for the number of events below pH of 5.5, 5.0, 4.5, and 4.0 per 24-hour period were 16.6, 10.7, 7.4, and 0.2, respectively. The upper limits of normal (95th percentile) for an acid exposure time below pH of 5.5, 5.0, 4.5, and 4.0 per 24-hour period were 820 seconds, 385 seconds, 75 seconds, and 3 seconds, respectively. Conclusions: Normative pharyngeal pH values are presented. Further studies are required to determine clinical relevance.

KW - Extraesophageal reflux

KW - Laryngopharyngeal reflux

KW - PH monitor

UR - http://www.scopus.com/inward/record.url?scp=62449289121&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=62449289121&partnerID=8YFLogxK

U2 - 10.1177/000348940911800302

DO - 10.1177/000348940911800302

M3 - Article

VL - 118

SP - 166

EP - 171

JO - Annals of Otology, Rhinology and Laryngology

JF - Annals of Otology, Rhinology and Laryngology

SN - 0003-4894

IS - 3

ER -