TY - JOUR
T1 - Normal values for pharyngeal pH monitoring
AU - Chheda, Neil N.
AU - Seybt, Melanie W.
AU - Schade, Robert R.
AU - Postma, Gregory N.
N1 - Funding Information:
From the Department of Otolaryngology, University of Florida, Gainesville, Florida (Chheda), and the Center for Voice and Swallowing Disorders, Department of Otolaryngology (Seybt, Postma), and the Department of Medicine, Section of Gastroenterology (Schade), Medical College of Georgia, Augusta, Georgia. The Respiratory Technology Corporation provided financial support for this study. Dr Postma is on the Scientific Advisory Board of the Respiratory Technology Corporation.
PY - 2009/3
Y1 - 2009/3
N2 - Objectives: We performed a prospective study of asymptomatic adult volunteers to establish normative values of pharyngeal pH using a novel pH probe. Methods: The Dx-pH probe is a novel pH device capable of measuring liquid and aerosolized acid levels. Twenty asymptomatic patients (Reflux Symptom Index less than 10 and Reflux Finding Score less than 6) underwent simultaneous investigation with this probe placed in the oropharynx and a dual antimony probe placed in the hypopharynx and esophagus. The reflux parameters measured from the oropharyngeal probe included the percentage of time and the number of events in which the pH was less than 5.5, 5.0, 4.5, and 4.0. Results: The upper limits of normal (95th percentile) for the number of events below pH of 5.5, 5.0, 4.5, and 4.0 per 24-hour period were 16.6, 10.7, 7.4, and 0.2, respectively. The upper limits of normal (95th percentile) for an acid exposure time below pH of 5.5, 5.0, 4.5, and 4.0 per 24-hour period were 820 seconds, 385 seconds, 75 seconds, and 3 seconds, respectively. Conclusions: Normative pharyngeal pH values are presented. Further studies are required to determine clinical relevance.
AB - Objectives: We performed a prospective study of asymptomatic adult volunteers to establish normative values of pharyngeal pH using a novel pH probe. Methods: The Dx-pH probe is a novel pH device capable of measuring liquid and aerosolized acid levels. Twenty asymptomatic patients (Reflux Symptom Index less than 10 and Reflux Finding Score less than 6) underwent simultaneous investigation with this probe placed in the oropharynx and a dual antimony probe placed in the hypopharynx and esophagus. The reflux parameters measured from the oropharyngeal probe included the percentage of time and the number of events in which the pH was less than 5.5, 5.0, 4.5, and 4.0. Results: The upper limits of normal (95th percentile) for the number of events below pH of 5.5, 5.0, 4.5, and 4.0 per 24-hour period were 16.6, 10.7, 7.4, and 0.2, respectively. The upper limits of normal (95th percentile) for an acid exposure time below pH of 5.5, 5.0, 4.5, and 4.0 per 24-hour period were 820 seconds, 385 seconds, 75 seconds, and 3 seconds, respectively. Conclusions: Normative pharyngeal pH values are presented. Further studies are required to determine clinical relevance.
KW - Extraesophageal reflux
KW - Laryngopharyngeal reflux
KW - PH monitor
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U2 - 10.1177/000348940911800302
DO - 10.1177/000348940911800302
M3 - Article
C2 - 19374146
AN - SCOPUS:62449289121
SN - 0003-4894
VL - 118
SP - 166
EP - 171
JO - Annals of Otology, Rhinology and Laryngology
JF - Annals of Otology, Rhinology and Laryngology
IS - 3
ER -