Optimal section thickness for detection of polyps at MR: resolution phantom study

Courtney C. Moreno, Pardeep K. Mittal, Nicholas L. Henson, Deborah A. Baumgarten, Lauren F. Alexander, Timothy S. Hanes, William C. Small, Hiroumi D. Kitajima, Jian Kang, John R. Votaw, John N. Oshinski, W. Thomas Dixon

Research output: Contribution to journalArticle

Abstract

Purpose: To determine (1) the sensitivity for detection of small polyps with varying MR slice thicknesses using a resolution phantom; (2) reader confidence in polyp detection; and (3) image acquisition time. Methods: A resolution phantom was created using a 3D printer. Polyp morphologies were sessile (height = diameter), flat (height = 1/2 diameter of the base), and pedunculated (stalk length = polyp diameter). Polyp diameters were 5, 7, 10, and 12 mm. Images were acquired with section thicknesses of 5, 3, and 1 mm. Images were independently reviewed by 4 board-certified radiologists who were blinded to phantom design and sequences parameters. Readers recorded maximal polyp diameter and confidence level that a polyp was present on a 1–100 point scale. Image acquisition time was also recorded. Results: All polyps were detected by all 4 readers in the 5-mm-section thickness series. All polyps were detected by 3 readers in the 3- and 1-mm-section thickness series. The fourth reader identified 11/12 polyps in the 3- and 1-mm-section thickness series. Confidence levels were not statistically significantly different for the different section thicknesses (p = 0.28). Increasing the section thickness from 1 to 5 mm decreased image acquisition time from 3 min 54 s to 41 s. Conclusions: Five-millimeter-section thickness was adequate for identification of 5–12 mm polyps regardless of shape. Pending further reduction in acquisition time, this prototype sequence holds promise for segmental imaging of the colon with MR colonography.

Original languageEnglish (US)
Pages (from-to)1451-1456
Number of pages6
JournalAbdominal Imaging
Volume40
Issue number6
DOIs
StatePublished - Aug 12 2015

Fingerprint

Polyps
Colon

Keywords

  • Colonic polyps
  • Colorectal cancer
  • Magnetic resonance colonography
  • Magnetic resonance imaging

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology
  • Radiology Nuclear Medicine and imaging
  • Gastroenterology
  • Urology

Cite this

Moreno, C. C., Mittal, P. K., Henson, N. L., Baumgarten, D. A., Alexander, L. F., Hanes, T. S., ... Dixon, W. T. (2015). Optimal section thickness for detection of polyps at MR: resolution phantom study. Abdominal Imaging, 40(6), 1451-1456. https://doi.org/10.1007/s00261-014-0331-6

Optimal section thickness for detection of polyps at MR : resolution phantom study. / Moreno, Courtney C.; Mittal, Pardeep K.; Henson, Nicholas L.; Baumgarten, Deborah A.; Alexander, Lauren F.; Hanes, Timothy S.; Small, William C.; Kitajima, Hiroumi D.; Kang, Jian; Votaw, John R.; Oshinski, John N.; Dixon, W. Thomas.

In: Abdominal Imaging, Vol. 40, No. 6, 12.08.2015, p. 1451-1456.

Research output: Contribution to journalArticle

Moreno, CC, Mittal, PK, Henson, NL, Baumgarten, DA, Alexander, LF, Hanes, TS, Small, WC, Kitajima, HD, Kang, J, Votaw, JR, Oshinski, JN & Dixon, WT 2015, 'Optimal section thickness for detection of polyps at MR: resolution phantom study', Abdominal Imaging, vol. 40, no. 6, pp. 1451-1456. https://doi.org/10.1007/s00261-014-0331-6
Moreno CC, Mittal PK, Henson NL, Baumgarten DA, Alexander LF, Hanes TS et al. Optimal section thickness for detection of polyps at MR: resolution phantom study. Abdominal Imaging. 2015 Aug 12;40(6):1451-1456. https://doi.org/10.1007/s00261-014-0331-6
Moreno, Courtney C. ; Mittal, Pardeep K. ; Henson, Nicholas L. ; Baumgarten, Deborah A. ; Alexander, Lauren F. ; Hanes, Timothy S. ; Small, William C. ; Kitajima, Hiroumi D. ; Kang, Jian ; Votaw, John R. ; Oshinski, John N. ; Dixon, W. Thomas. / Optimal section thickness for detection of polyps at MR : resolution phantom study. In: Abdominal Imaging. 2015 ; Vol. 40, No. 6. pp. 1451-1456.
@article{f0af30a08bce48208edabe0ec2361d1b,
title = "Optimal section thickness for detection of polyps at MR: resolution phantom study",
abstract = "Purpose: To determine (1) the sensitivity for detection of small polyps with varying MR slice thicknesses using a resolution phantom; (2) reader confidence in polyp detection; and (3) image acquisition time. Methods: A resolution phantom was created using a 3D printer. Polyp morphologies were sessile (height = diameter), flat (height = 1/2 diameter of the base), and pedunculated (stalk length = polyp diameter). Polyp diameters were 5, 7, 10, and 12 mm. Images were acquired with section thicknesses of 5, 3, and 1 mm. Images were independently reviewed by 4 board-certified radiologists who were blinded to phantom design and sequences parameters. Readers recorded maximal polyp diameter and confidence level that a polyp was present on a 1–100 point scale. Image acquisition time was also recorded. Results: All polyps were detected by all 4 readers in the 5-mm-section thickness series. All polyps were detected by 3 readers in the 3- and 1-mm-section thickness series. The fourth reader identified 11/12 polyps in the 3- and 1-mm-section thickness series. Confidence levels were not statistically significantly different for the different section thicknesses (p = 0.28). Increasing the section thickness from 1 to 5 mm decreased image acquisition time from 3 min 54 s to 41 s. Conclusions: Five-millimeter-section thickness was adequate for identification of 5–12 mm polyps regardless of shape. Pending further reduction in acquisition time, this prototype sequence holds promise for segmental imaging of the colon with MR colonography.",
keywords = "Colonic polyps, Colorectal cancer, Magnetic resonance colonography, Magnetic resonance imaging",
author = "Moreno, {Courtney C.} and Mittal, {Pardeep K.} and Henson, {Nicholas L.} and Baumgarten, {Deborah A.} and Alexander, {Lauren F.} and Hanes, {Timothy S.} and Small, {William C.} and Kitajima, {Hiroumi D.} and Jian Kang and Votaw, {John R.} and Oshinski, {John N.} and Dixon, {W. Thomas}",
year = "2015",
month = "8",
day = "12",
doi = "10.1007/s00261-014-0331-6",
language = "English (US)",
volume = "40",
pages = "1451--1456",
journal = "Abdominal Radiology",
issn = "2366-004X",
publisher = "Springer New York",
number = "6",

}

TY - JOUR

T1 - Optimal section thickness for detection of polyps at MR

T2 - resolution phantom study

AU - Moreno, Courtney C.

AU - Mittal, Pardeep K.

AU - Henson, Nicholas L.

AU - Baumgarten, Deborah A.

AU - Alexander, Lauren F.

AU - Hanes, Timothy S.

AU - Small, William C.

AU - Kitajima, Hiroumi D.

AU - Kang, Jian

AU - Votaw, John R.

AU - Oshinski, John N.

AU - Dixon, W. Thomas

PY - 2015/8/12

Y1 - 2015/8/12

N2 - Purpose: To determine (1) the sensitivity for detection of small polyps with varying MR slice thicknesses using a resolution phantom; (2) reader confidence in polyp detection; and (3) image acquisition time. Methods: A resolution phantom was created using a 3D printer. Polyp morphologies were sessile (height = diameter), flat (height = 1/2 diameter of the base), and pedunculated (stalk length = polyp diameter). Polyp diameters were 5, 7, 10, and 12 mm. Images were acquired with section thicknesses of 5, 3, and 1 mm. Images were independently reviewed by 4 board-certified radiologists who were blinded to phantom design and sequences parameters. Readers recorded maximal polyp diameter and confidence level that a polyp was present on a 1–100 point scale. Image acquisition time was also recorded. Results: All polyps were detected by all 4 readers in the 5-mm-section thickness series. All polyps were detected by 3 readers in the 3- and 1-mm-section thickness series. The fourth reader identified 11/12 polyps in the 3- and 1-mm-section thickness series. Confidence levels were not statistically significantly different for the different section thicknesses (p = 0.28). Increasing the section thickness from 1 to 5 mm decreased image acquisition time from 3 min 54 s to 41 s. Conclusions: Five-millimeter-section thickness was adequate for identification of 5–12 mm polyps regardless of shape. Pending further reduction in acquisition time, this prototype sequence holds promise for segmental imaging of the colon with MR colonography.

AB - Purpose: To determine (1) the sensitivity for detection of small polyps with varying MR slice thicknesses using a resolution phantom; (2) reader confidence in polyp detection; and (3) image acquisition time. Methods: A resolution phantom was created using a 3D printer. Polyp morphologies were sessile (height = diameter), flat (height = 1/2 diameter of the base), and pedunculated (stalk length = polyp diameter). Polyp diameters were 5, 7, 10, and 12 mm. Images were acquired with section thicknesses of 5, 3, and 1 mm. Images were independently reviewed by 4 board-certified radiologists who were blinded to phantom design and sequences parameters. Readers recorded maximal polyp diameter and confidence level that a polyp was present on a 1–100 point scale. Image acquisition time was also recorded. Results: All polyps were detected by all 4 readers in the 5-mm-section thickness series. All polyps were detected by 3 readers in the 3- and 1-mm-section thickness series. The fourth reader identified 11/12 polyps in the 3- and 1-mm-section thickness series. Confidence levels were not statistically significantly different for the different section thicknesses (p = 0.28). Increasing the section thickness from 1 to 5 mm decreased image acquisition time from 3 min 54 s to 41 s. Conclusions: Five-millimeter-section thickness was adequate for identification of 5–12 mm polyps regardless of shape. Pending further reduction in acquisition time, this prototype sequence holds promise for segmental imaging of the colon with MR colonography.

KW - Colonic polyps

KW - Colorectal cancer

KW - Magnetic resonance colonography

KW - Magnetic resonance imaging

UR - http://www.scopus.com/inward/record.url?scp=84938974069&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84938974069&partnerID=8YFLogxK

U2 - 10.1007/s00261-014-0331-6

DO - 10.1007/s00261-014-0331-6

M3 - Article

C2 - 25504518

AN - SCOPUS:84938974069

VL - 40

SP - 1451

EP - 1456

JO - Abdominal Radiology

JF - Abdominal Radiology

SN - 2366-004X

IS - 6

ER -