Ovarian surgery on the rabbit: Effect of cortex closure on adhesion formation and ovarian function

W. R. Meyer; D. A. Grainger; A. H. DeCherney; M. S. Lachs; M. P. Diamond

Ovarian surgery on the rabbit: Effect of cortex closure on adhesion formation and ovarian function

W. R. Meyer, D. A. Grainger, A. H. DeCherney, M. S. Lachs, M. P. Diamond

Research output: Contribution to journal › Article › peer-review

Abstract

Surgical reapproximation of serosal surfaces in an attempt to reduce adhesiogenesis remains a controversial issue. For the reproductive gynecologist, this tenet is especially appropriate to the ovarian cortical surface. Using a rabbit model (n = 22), an ovarian unipolar cautery incision was created, and surgical closure versus nonclosure was evaluated. Closure with continuous 6-0 polyglactin resulted in a significant increase in the degree of ovarian adhesion envelopment versus nonclosure (1.8±0.2 vs. 0.9±0.2, P < .01). Surgical closure also resulted in a significant increase in the vascularity of the adhesions (P < .05). Despite the increase in adhesion formation, ovarian function, as determined by the mean number of corpora lutea, pregnancies and the nidation index, was not different in sutured ovaries, unsutured ovaries or nonsurgically treated controls.

Original language	English (US)
Pages (from-to)	639-643
Number of pages	5
Journal	Journal of Reproductive Medicine for the Obstetrician and Gynecologist
Volume	36
Issue number	9
State	Published - Jan 1 1991
Externally published	Yes

ASJC Scopus subject areas

Reproductive Medicine
Obstetrics and Gynecology

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abstract = "Surgical reapproximation of serosal surfaces in an attempt to reduce adhesiogenesis remains a controversial issue. For the reproductive gynecologist, this tenet is especially appropriate to the ovarian cortical surface. Using a rabbit model (n = 22), an ovarian unipolar cautery incision was created, and surgical closure versus nonclosure was evaluated. Closure with continuous 6-0 polyglactin resulted in a significant increase in the degree of ovarian adhesion envelopment versus nonclosure (1.8±0.2 vs. 0.9±0.2, P < .01). Surgical closure also resulted in a significant increase in the vascularity of the adhesions (P < .05). Despite the increase in adhesion formation, ovarian function, as determined by the mean number of corpora lutea, pregnancies and the nidation index, was not different in sutured ovaries, unsutured ovaries or nonsurgically treated controls.",

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T2 - Effect of cortex closure on adhesion formation and ovarian function

AU - Meyer, W. R.

AU - Grainger, D. A.

AU - DeCherney, A. H.

AU - Lachs, M. S.

AU - Diamond, M. P.

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AB - Surgical reapproximation of serosal surfaces in an attempt to reduce adhesiogenesis remains a controversial issue. For the reproductive gynecologist, this tenet is especially appropriate to the ovarian cortical surface. Using a rabbit model (n = 22), an ovarian unipolar cautery incision was created, and surgical closure versus nonclosure was evaluated. Closure with continuous 6-0 polyglactin resulted in a significant increase in the degree of ovarian adhesion envelopment versus nonclosure (1.8±0.2 vs. 0.9±0.2, P < .01). Surgical closure also resulted in a significant increase in the vascularity of the adhesions (P < .05). Despite the increase in adhesion formation, ovarian function, as determined by the mean number of corpora lutea, pregnancies and the nidation index, was not different in sutured ovaries, unsutured ovaries or nonsurgically treated controls.

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