Abstract
Introduction: We attempted to replicate two previous studies which found an increased risk of diabetes in the relatives of schizophrenia probands. Methods: N = 34 patients with newly-diagnosed nonaffective psychosis and N = 52 non-psychiatric controls were interviewed for parental history of Type 2 diabetes. Results: In a logistic regression model that included multiple potential confounders, psychosis was a significant predictor of Type 2 diabetes in either parent (p < 0.04). Discussion: We found an increased prevalence of Type 2 diabetes in the parents of nonaffective psychosis subjects. This association may be due to shared environmental or genetic risk factors, or both.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 302-306 |
| Number of pages | 5 |
| Journal | Schizophrenia Research |
| Volume | 98 |
| Issue number | 1-3 |
| DOIs | |
| State | Published - Jan 1 2008 |
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Keywords
- Epidemiology
- Family history
- Nonaffective psychosis
- Schizophrenia
- Type 2 diabetes
ASJC Scopus subject areas
- Psychiatry and Mental health
- Biological Psychiatry
Cite this
Parental history of Type 2 diabetes in patients with nonaffective psychosis. / Fernandez-Egea, Emilio; Miller, Brian J; Bernardo, Miguel; Donner, Thomas; Kirkpatrick, Brian.
In: Schizophrenia Research, Vol. 98, No. 1-3, 01.01.2008, p. 302-306.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Parental history of Type 2 diabetes in patients with nonaffective psychosis
AU - Fernandez-Egea, Emilio
AU - Miller, Brian J
AU - Bernardo, Miguel
AU - Donner, Thomas
AU - Kirkpatrick, Brian
PY - 2008/1/1
Y1 - 2008/1/1
N2 - Introduction: We attempted to replicate two previous studies which found an increased risk of diabetes in the relatives of schizophrenia probands. Methods: N = 34 patients with newly-diagnosed nonaffective psychosis and N = 52 non-psychiatric controls were interviewed for parental history of Type 2 diabetes. Results: In a logistic regression model that included multiple potential confounders, psychosis was a significant predictor of Type 2 diabetes in either parent (p < 0.04). Discussion: We found an increased prevalence of Type 2 diabetes in the parents of nonaffective psychosis subjects. This association may be due to shared environmental or genetic risk factors, or both.
AB - Introduction: We attempted to replicate two previous studies which found an increased risk of diabetes in the relatives of schizophrenia probands. Methods: N = 34 patients with newly-diagnosed nonaffective psychosis and N = 52 non-psychiatric controls were interviewed for parental history of Type 2 diabetes. Results: In a logistic regression model that included multiple potential confounders, psychosis was a significant predictor of Type 2 diabetes in either parent (p < 0.04). Discussion: We found an increased prevalence of Type 2 diabetes in the parents of nonaffective psychosis subjects. This association may be due to shared environmental or genetic risk factors, or both.
KW - Epidemiology
KW - Family history
KW - Nonaffective psychosis
KW - Schizophrenia
KW - Type 2 diabetes
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UR - http://www.scopus.com/inward/citedby.url?scp=37049024526&partnerID=8YFLogxK
U2 - 10.1016/j.schres.2007.10.002
DO - 10.1016/j.schres.2007.10.002
M3 - Article
C2 - 18031995
AN - SCOPUS:37049024526
VL - 98
SP - 302
EP - 306
JO - Schizophrenia Research
JF - Schizophrenia Research
SN - 0920-9964
IS - 1-3
ER -