Parental history of Type 2 diabetes in patients with nonaffective psychosis

Emilio Fernandez-Egea, Brian J Miller, Miguel Bernardo, Thomas Donner, Brian Kirkpatrick

Research output: Contribution to journalArticle

56 Citations (Scopus)

Abstract

Introduction: We attempted to replicate two previous studies which found an increased risk of diabetes in the relatives of schizophrenia probands. Methods: N = 34 patients with newly-diagnosed nonaffective psychosis and N = 52 non-psychiatric controls were interviewed for parental history of Type 2 diabetes. Results: In a logistic regression model that included multiple potential confounders, psychosis was a significant predictor of Type 2 diabetes in either parent (p < 0.04). Discussion: We found an increased prevalence of Type 2 diabetes in the parents of nonaffective psychosis subjects. This association may be due to shared environmental or genetic risk factors, or both.

Original languageEnglish (US)
Pages (from-to)302-306
Number of pages5
JournalSchizophrenia Research
Volume98
Issue number1-3
DOIs
StatePublished - Jan 1 2008

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Psychotic Disorders
Type 2 Diabetes Mellitus
Logistic Models
Schizophrenia
Parents

Keywords

  • Epidemiology
  • Family history
  • Nonaffective psychosis
  • Schizophrenia
  • Type 2 diabetes

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Biological Psychiatry

Cite this

Parental history of Type 2 diabetes in patients with nonaffective psychosis. / Fernandez-Egea, Emilio; Miller, Brian J; Bernardo, Miguel; Donner, Thomas; Kirkpatrick, Brian.

In: Schizophrenia Research, Vol. 98, No. 1-3, 01.01.2008, p. 302-306.

Research output: Contribution to journalArticle

Fernandez-Egea, E, Miller, BJ, Bernardo, M, Donner, T & Kirkpatrick, B 2008, 'Parental history of Type 2 diabetes in patients with nonaffective psychosis', Schizophrenia Research, vol. 98, no. 1-3, pp. 302-306. https://doi.org/10.1016/j.schres.2007.10.002
Fernandez-Egea, Emilio ; Miller, Brian J ; Bernardo, Miguel ; Donner, Thomas ; Kirkpatrick, Brian. / Parental history of Type 2 diabetes in patients with nonaffective psychosis. In: Schizophrenia Research. 2008 ; Vol. 98, No. 1-3. pp. 302-306.
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