Abstract
Introduction: We attempted to replicate two previous studies which found an increased risk of diabetes in the relatives of schizophrenia probands. Methods: N = 34 patients with newly-diagnosed nonaffective psychosis and N = 52 non-psychiatric controls were interviewed for parental history of Type 2 diabetes. Results: In a logistic regression model that included multiple potential confounders, psychosis was a significant predictor of Type 2 diabetes in either parent (p < 0.04). Discussion: We found an increased prevalence of Type 2 diabetes in the parents of nonaffective psychosis subjects. This association may be due to shared environmental or genetic risk factors, or both.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 302-306 |
| Number of pages | 5 |
| Journal | Schizophrenia Research |
| Volume | 98 |
| Issue number | 1-3 |
| DOIs | |
| State | Published - Jan 1 2008 |
Keywords
- Epidemiology
- Family history
- Nonaffective psychosis
- Schizophrenia
- Type 2 diabetes
ASJC Scopus subject areas
- Psychiatry and Mental health
- Biological Psychiatry
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Fernandez-Egea, E., Miller, B. J., Bernardo, M., Donner, T., & Kirkpatrick, B. (2008). Parental history of Type 2 diabetes in patients with nonaffective psychosis. Schizophrenia Research, 98(1-3), 302-306. https://doi.org/10.1016/j.schres.2007.10.002