Parental history of Type 2 diabetes in patients with nonaffective psychosis

Emilio Fernandez-Egea; Brian J Miller; Miguel Bernardo; Thomas Donner; Brian Kirkpatrick

doi:10.1016/j.schres.2007.10.002

Parental history of Type 2 diabetes in patients with nonaffective psychosis

Emilio Fernandez-Egea, Brian J Miller, Miguel Bernardo, Thomas Donner, Brian Kirkpatrick

Psychiatry and Health Behavior

Research output: Contribution to journal › Article › peer-review

70 Scopus citations

Abstract

Introduction: We attempted to replicate two previous studies which found an increased risk of diabetes in the relatives of schizophrenia probands. Methods: N = 34 patients with newly-diagnosed nonaffective psychosis and N = 52 non-psychiatric controls were interviewed for parental history of Type 2 diabetes. Results: In a logistic regression model that included multiple potential confounders, psychosis was a significant predictor of Type 2 diabetes in either parent (p < 0.04). Discussion: We found an increased prevalence of Type 2 diabetes in the parents of nonaffective psychosis subjects. This association may be due to shared environmental or genetic risk factors, or both.

Original language	English (US)
Pages (from-to)	302-306
Number of pages	5
Journal	Schizophrenia Research
Volume	98
Issue number	1-3
DOIs	https://doi.org/10.1016/j.schres.2007.10.002
State	Published - Jan 2008

Keywords

Epidemiology
Family history
Nonaffective psychosis
Schizophrenia
Type 2 diabetes

ASJC Scopus subject areas

Psychiatry and Mental health
Biological Psychiatry

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1016/j.schres.2007.10.002

Cite this

@article{cffe4f92592e4cfea4ccc346d7152871,

title = "Parental history of Type 2 diabetes in patients with nonaffective psychosis",

abstract = "Introduction: We attempted to replicate two previous studies which found an increased risk of diabetes in the relatives of schizophrenia probands. Methods: N = 34 patients with newly-diagnosed nonaffective psychosis and N = 52 non-psychiatric controls were interviewed for parental history of Type 2 diabetes. Results: In a logistic regression model that included multiple potential confounders, psychosis was a significant predictor of Type 2 diabetes in either parent (p < 0.04). Discussion: We found an increased prevalence of Type 2 diabetes in the parents of nonaffective psychosis subjects. This association may be due to shared environmental or genetic risk factors, or both.",

keywords = "Epidemiology, Family history, Nonaffective psychosis, Schizophrenia, Type 2 diabetes",

author = "Emilio Fernandez-Egea and Miller, {Brian J} and Miguel Bernardo and Thomas Donner and Brian Kirkpatrick",

year = "2008",

month = jan,

doi = "10.1016/j.schres.2007.10.002",

language = "English (US)",

volume = "98",

pages = "302--306",

journal = "Schizophrenia Research",

issn = "0920-9964",

publisher = "Elsevier",

number = "1-3",

}

TY - JOUR

T1 - Parental history of Type 2 diabetes in patients with nonaffective psychosis

AU - Fernandez-Egea, Emilio

AU - Miller, Brian J

AU - Bernardo, Miguel

AU - Donner, Thomas

AU - Kirkpatrick, Brian

PY - 2008/1

Y1 - 2008/1

N2 - Introduction: We attempted to replicate two previous studies which found an increased risk of diabetes in the relatives of schizophrenia probands. Methods: N = 34 patients with newly-diagnosed nonaffective psychosis and N = 52 non-psychiatric controls were interviewed for parental history of Type 2 diabetes. Results: In a logistic regression model that included multiple potential confounders, psychosis was a significant predictor of Type 2 diabetes in either parent (p < 0.04). Discussion: We found an increased prevalence of Type 2 diabetes in the parents of nonaffective psychosis subjects. This association may be due to shared environmental or genetic risk factors, or both.

AB - Introduction: We attempted to replicate two previous studies which found an increased risk of diabetes in the relatives of schizophrenia probands. Methods: N = 34 patients with newly-diagnosed nonaffective psychosis and N = 52 non-psychiatric controls were interviewed for parental history of Type 2 diabetes. Results: In a logistic regression model that included multiple potential confounders, psychosis was a significant predictor of Type 2 diabetes in either parent (p < 0.04). Discussion: We found an increased prevalence of Type 2 diabetes in the parents of nonaffective psychosis subjects. This association may be due to shared environmental or genetic risk factors, or both.

KW - Epidemiology

KW - Family history

KW - Nonaffective psychosis

KW - Schizophrenia

KW - Type 2 diabetes

UR - http://www.scopus.com/inward/record.url?scp=37049024526&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=37049024526&partnerID=8YFLogxK

U2 - 10.1016/j.schres.2007.10.002

DO - 10.1016/j.schres.2007.10.002

M3 - Article

C2 - 18031995

AN - SCOPUS:37049024526

SN - 0920-9964

VL - 98

SP - 302

EP - 306

JO - Schizophrenia Research

JF - Schizophrenia Research

IS - 1-3

ER -

Parental history of Type 2 diabetes in patients with nonaffective psychosis

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this