Periodontal disease

links with serum lipid/ triglyceride levels? Review and new data.

Christopher W Cutler, Anthony M. Iacopino

Research output: Contribution to journalReview article

31 Citations (Scopus)

Abstract

Evidence now supports an intriguing role for serum lipids/triglycerides in modulation of the host immune response to infection. This paper will review the studies that have been conducted in humans and various animal models of the association between elevated serum lipids/triglycerides (i.e. hyperlipidaemia) and periodontitis (PD). We will also present new data in rats that suggests a bi-directional relationship between hyperlipidaemia and PD, i.e. that PD itself may be able to modulate serum lipid levels. This review will introduce evidence from other studies that the type of dietary lipids is important in the modulation of the immune/inflammatory response. Overall, the studies presented herein suggest that further investigation using epidemiological and experimental approaches is warranted.

Original languageEnglish (US)
Pages (from-to)47-51
Number of pages5
JournalJournal of the International Academy of Periodontology
Volume5
Issue number2
StatePublished - Jan 1 2003
Externally publishedYes

Fingerprint

Periodontal Diseases
Periodontitis
Triglycerides
Lipids
Hyperlipidemias
Serum
Animal Models
Infection

Cite this

Periodontal disease : links with serum lipid/ triglyceride levels? Review and new data. / Cutler, Christopher W; Iacopino, Anthony M.

In: Journal of the International Academy of Periodontology, Vol. 5, No. 2, 01.01.2003, p. 47-51.

Research output: Contribution to journalReview article

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