Periodontal repair in dogs: effect of a composite graft protocol on healing in supraalveolar periodontal defects.

U. M. Wikesjö, G. C. Bogle, R. E. Nilvéus

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

This study evaluated the effect of a composite graft as an adjunct to gingival flap surgery in induced chronic supraalveolar periodontal defects in the mandibular premolar region in beagle dogs. The vertical dimension of the defects, measured from the cemento-enamel junction to the alveolar bone, approximated 5 mm. Root surface treatment in quadrants receiving the graft protocol included conditioning with both critic acid and tetracycline. The composite graft (including: hydroxyapatite, freeze-dried decalcified bone, tetracycline, and fibronectin) was then fitted to the defects. Flaps were placed and sutured to cover most of the crowns of the teeth but the tips of the cusps. The root surfaces in contralateral jaw quadrants were conditioned with critic acid and the flaps similarly placed and sutured. Dogs were sacrificed 6 weeks after surgery and tissue blocks including teeth and surrounding structures processed for histometric analysis. Connective tissue repair to the root surface in teeth treated with the graft protocol approximated 60% of the defect height. Connective tissue repair in teeth treated with citric acid only was significantly greater and averaged 98% of the defect height (P less than or equal to 0.01). Cementum formation was limited following both treatments (approximately 6% of the defect height). Bone regeneration was significantly smaller in grafted sites than in sites treated with citric acid only (approximately 2% and 10% of the defect height, respectively; P less than or equal to 0.05). Root resorption was observed in almost all teeth. Ankylosis was present in two citric acid-treated specimens, both from the same dog.(ABSTRACT TRUNCATED AT 250 WORDS)

Original languageEnglish (US)
Pages (from-to)107-113
Number of pages7
JournalJournal of Periodontology
Volume63
Issue number2
DOIs
StatePublished - Jan 1 1992

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Tooth
Citric Acid
Dogs
Transplants
Tetracycline
Connective Tissue
Tooth Crown
Vertical Dimension
Root Resorption
Dental Cementum
Ankylosis
Bone and Bones
Bone Regeneration
Acids
Bicuspid
Durapatite
Dental Enamel
Jaw
Fibronectins

ASJC Scopus subject areas

  • Periodontics

Cite this

Periodontal repair in dogs : effect of a composite graft protocol on healing in supraalveolar periodontal defects. / Wikesjö, U. M.; Bogle, G. C.; Nilvéus, R. E.

In: Journal of Periodontology, Vol. 63, No. 2, 01.01.1992, p. 107-113.

Research output: Contribution to journalArticle

Wikesjö, U. M. ; Bogle, G. C. ; Nilvéus, R. E. / Periodontal repair in dogs : effect of a composite graft protocol on healing in supraalveolar periodontal defects. In: Journal of Periodontology. 1992 ; Vol. 63, No. 2. pp. 107-113.
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