A 20-year-old man with confirmed Hunter syndrome had entrapments of median and ulnar nerves. Sural nerve biopsy specimen revealed clear, lamellated, and granular inclusions in Schwann cells, fibroblasts, and perineurial cells. The clear inclusions are believed to represent storage of mucopolysaccharide, and the zebra bodies, ganglioside. Focal alterations in myelin were found, associated with moderately dense granular inclusions. Following carpal tunnel release operations, the patient experienced dramatic relief of symptoms.
|Original language||English (US)|
|Number of pages||2|
|Journal||Archives of Neurology|
|Publication status||Published - Dec 1976|
ASJC Scopus subject areas
- Arts and Humanities (miscellaneous)
- Clinical Neurology