Plasmapheresis for fulminant meningococcemia

M. S. Drapkin, J. S. Wisch, J. A. Gelfand, J. G. Cannon, C. A. Dinarello

Research output: Contribution to journalArticle

45 Scopus citations


Fulminant meningococcemia remains one of the most frightening and lethal of infections, capable of resulting in death within hours. Reports of the use of plasmapheresis in a few patients with the syndrome prompted us to utilize that technique recently in a severely ill patient. Improvement correlated with dropping plasma concentrations of tumor necrosis factor alpha (TNF) and of interleukin 1-beta (IL-1), suggesting a possible rationale for such treatment.

Original languageEnglish (US)
Pages (from-to)399-400
Number of pages2
JournalPediatric Infectious Disease Journal
Issue number6
StatePublished - Jan 1 1989

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Microbiology (medical)
  • Infectious Diseases

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    Drapkin, M. S., Wisch, J. S., Gelfand, J. A., Cannon, J. G., & Dinarello, C. A. (1989). Plasmapheresis for fulminant meningococcemia. Pediatric Infectious Disease Journal, 8(6), 399-400.