Plasmapheresis for fulminant meningococcemia

M. S. Drapkin, J. S. Wisch, J. A. Gelfand, J. G. Cannon, C. A. Dinarello

Research output: Contribution to journalArticle

45 Citations (Scopus)

Abstract

Fulminant meningococcemia remains one of the most frightening and lethal of infections, capable of resulting in death within hours. Reports of the use of plasmapheresis in a few patients with the syndrome prompted us to utilize that technique recently in a severely ill patient. Improvement correlated with dropping plasma concentrations of tumor necrosis factor alpha (TNF) and of interleukin 1-beta (IL-1), suggesting a possible rationale for such treatment.

Original languageEnglish (US)
Pages (from-to)399-400
Number of pages2
JournalPediatric Infectious Disease Journal
Volume8
Issue number6
DOIs
StatePublished - Jan 1 1989

Fingerprint

Plasmapheresis
Interleukin-1beta
Tumor Necrosis Factor-alpha
Infection
Therapeutics

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Microbiology (medical)
  • Infectious Diseases

Cite this

Drapkin, M. S., Wisch, J. S., Gelfand, J. A., Cannon, J. G., & Dinarello, C. A. (1989). Plasmapheresis for fulminant meningococcemia. Pediatric Infectious Disease Journal, 8(6), 399-400. https://doi.org/10.1097/00006454-198906000-00015

Plasmapheresis for fulminant meningococcemia. / Drapkin, M. S.; Wisch, J. S.; Gelfand, J. A.; Cannon, J. G.; Dinarello, C. A.

In: Pediatric Infectious Disease Journal, Vol. 8, No. 6, 01.01.1989, p. 399-400.

Research output: Contribution to journalArticle

Drapkin, MS, Wisch, JS, Gelfand, JA, Cannon, JG & Dinarello, CA 1989, 'Plasmapheresis for fulminant meningococcemia', Pediatric Infectious Disease Journal, vol. 8, no. 6, pp. 399-400. https://doi.org/10.1097/00006454-198906000-00015
Drapkin MS, Wisch JS, Gelfand JA, Cannon JG, Dinarello CA. Plasmapheresis for fulminant meningococcemia. Pediatric Infectious Disease Journal. 1989 Jan 1;8(6):399-400. https://doi.org/10.1097/00006454-198906000-00015
Drapkin, M. S. ; Wisch, J. S. ; Gelfand, J. A. ; Cannon, J. G. ; Dinarello, C. A. / Plasmapheresis for fulminant meningococcemia. In: Pediatric Infectious Disease Journal. 1989 ; Vol. 8, No. 6. pp. 399-400.
@article{7c141e0effe345c1830f2554169ad49c,
title = "Plasmapheresis for fulminant meningococcemia",
abstract = "Fulminant meningococcemia remains one of the most frightening and lethal of infections, capable of resulting in death within hours. Reports of the use of plasmapheresis in a few patients with the syndrome prompted us to utilize that technique recently in a severely ill patient. Improvement correlated with dropping plasma concentrations of tumor necrosis factor alpha (TNF) and of interleukin 1-beta (IL-1), suggesting a possible rationale for such treatment.",
author = "Drapkin, {M. S.} and Wisch, {J. S.} and Gelfand, {J. A.} and Cannon, {J. G.} and Dinarello, {C. A.}",
year = "1989",
month = "1",
day = "1",
doi = "10.1097/00006454-198906000-00015",
language = "English (US)",
volume = "8",
pages = "399--400",
journal = "Pediatric Infectious Disease Journal",
issn = "0891-3668",
publisher = "Lippincott Williams and Wilkins",
number = "6",

}

TY - JOUR

T1 - Plasmapheresis for fulminant meningococcemia

AU - Drapkin, M. S.

AU - Wisch, J. S.

AU - Gelfand, J. A.

AU - Cannon, J. G.

AU - Dinarello, C. A.

PY - 1989/1/1

Y1 - 1989/1/1

N2 - Fulminant meningococcemia remains one of the most frightening and lethal of infections, capable of resulting in death within hours. Reports of the use of plasmapheresis in a few patients with the syndrome prompted us to utilize that technique recently in a severely ill patient. Improvement correlated with dropping plasma concentrations of tumor necrosis factor alpha (TNF) and of interleukin 1-beta (IL-1), suggesting a possible rationale for such treatment.

AB - Fulminant meningococcemia remains one of the most frightening and lethal of infections, capable of resulting in death within hours. Reports of the use of plasmapheresis in a few patients with the syndrome prompted us to utilize that technique recently in a severely ill patient. Improvement correlated with dropping plasma concentrations of tumor necrosis factor alpha (TNF) and of interleukin 1-beta (IL-1), suggesting a possible rationale for such treatment.

UR - http://www.scopus.com/inward/record.url?scp=0024321151&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0024321151&partnerID=8YFLogxK

U2 - 10.1097/00006454-198906000-00015

DO - 10.1097/00006454-198906000-00015

M3 - Article

C2 - 2501752

AN - SCOPUS:0024321151

VL - 8

SP - 399

EP - 400

JO - Pediatric Infectious Disease Journal

JF - Pediatric Infectious Disease Journal

SN - 0891-3668

IS - 6

ER -