Potassium currents from isolated frog lens epithelial cells

Kim Cooper, Mitchell Watsky, James Rae

Research output: Contribution to journalArticle

4 Scopus citations

Abstract

Using the perforated patch version of whole-cell recording, we have measurd currents from isolated frog lens epithelial cells. Three types of currents were seen. A time-independent outwardly rectifying potassium current was identified that sets the resting voltage. This potassium current differs significantly from any of the potassium currents recorded with the whole-cell technique in mammalian lens epithelial cells. In addition to the potassium current, the two other currents present were both outwardly rectifying: one was time-independent while the other showed distinct activation.

Original languageEnglish (US)
Pages (from-to)861-868
Number of pages8
JournalExperimental eye research
Volume55
Issue number6
DOIs
StatePublished - Dec 1992
Externally publishedYes

Keywords

  • K current
  • frog lens epithelium
  • ion transport
  • patch clamp
  • resting voltage
  • voltage clamp

ASJC Scopus subject areas

  • Ophthalmology
  • Sensory Systems
  • Cellular and Molecular Neuroscience

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