Abstract
The enzymes responsible for performing cleavage of propeptides at basic amino acids have proven difficult to characterize. Using the processing of anglerfish islet prosomatostatin (PSS) as a model system, we are pursuing the characterization of both a single basic amino acid-specific and a dibasic amino acid-specific converting enzyme. We describe here the model system and protein isolation methods that have allowed significant progress toward complete characterization of the somatostatin-generating propeptide converting enzymes (PCEs).
Original language | English (US) |
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Pages (from-to) | 30-32 |
Number of pages | 3 |
Journal | Metabolism |
Volume | 39 |
Issue number | 9 SUPPL. 2 |
DOIs | |
State | Published - Sep 1990 |
Externally published | Yes |
ASJC Scopus subject areas
- Endocrinology, Diabetes and Metabolism
- Endocrinology