Abstract
Objectives: We evaluated the association of plasma uric acid alone and in combination with b-type natriuretic peptide (BNP) for emergency department (ED) diagnosis and 30-day prognosis in patients evaluated for acute heart failure (AHF). Methods: We prospectively enrolled 322 adult ED patients with suspected AHF. Wilcoxon rank sum test, multivariable logistic regression and likelihood ratio (LR) tests were used for statistical analyses. Results: Uric acid's diagnostic utility was poor and failed to show significant associations with 30-day clinical outcomes. Uric acid also did not add significantly to BNP results. Conclusion: Among ED patients with suspected AHF, uric acid has poor diagnostic and prognostic utility.
Original language | English (US) |
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Pages (from-to) | 9-15 |
Number of pages | 7 |
Journal | Open Biomarkers Journal |
Volume | 5 |
Issue number | 1 |
DOIs | |
State | Published - 2012 |
Keywords
- Acute heart failure
- B-type natriuretic peptide
- Prognostic outcomes
- Uric acid
ASJC Scopus subject areas
- Medicine (miscellaneous)
- Clinical Biochemistry
- Biochemistry, medical