An increased occurrence of salivary tumors was observed in 1922 patients who received radiation to the tonsils and nasopharynx. Twenty seven tumors, 19 benign and 8 malignant, were found in this group as compared with an expected 0.2 malignant < 1 benign tumor. The latent period between the initial radiation treatment and diagnosis ranged from 7 to 32 yr. After the first 15 yr the incidence (77 cases/105 subjects/yr) has remained constant and shows no indication of declining. Continued observation for salivary gland tumors is therefore indicated for subjects who received childhood irradiation.
ASJC Scopus subject areas
- Internal Medicine