Sapota fruit latex mediated synthesis of Ag, Cu mono and bimetallic nanoparticles and their in vitro toxicity studies

Sonal I. Thakore, Padamanabhi S. Nagar, Ravirajsinh N. Jadeja, Menaka Thounaojam, Ranjitsinh V. Devkar, Puran Singh Rathore

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Ag, Cu metallic and bimetallic nanoparticles (NPs) with diverse compositions were efficiently synthesized using the fruit latex of Achras sapota Linn. Spectroscopic and cyclic voltammetry results suggested that reduction of Ag was assisted by ascorbic acid, reducing sugars and other phenolic compounds present in the latex. However, the reduction of Cu and alloy NPs required additional ascorbic acid. Comparative in vitro toxicity of as synthesized nanoparticle solution was assessed in 3T3L1 cells using MTT assay and fluorescent microscopy. A minimal impact was observed on cell viability and morphology during 72 h. This demonstrates great potential for use in biomedical applications such as cellular imaging or photothermal therapy.

Original languageEnglish (US)
Pages (from-to)694-700
Number of pages7
JournalArabian Journal of Chemistry
Volume12
Issue number5
DOIs
StatePublished - Jul 1 2019

Fingerprint

Latex
Fruits
Latexes
Toxicity
Ascorbic acid
Nanoparticles
Ascorbic Acid
Sugars
Cyclic voltammetry
Assays
Microscopic examination
Cells
Imaging techniques
Chemical analysis

Keywords

  • Alloy nanoparticles
  • Cytotoxicity
  • Latex

ASJC Scopus subject areas

  • Chemistry(all)
  • Chemical Engineering(all)

Cite this

Sapota fruit latex mediated synthesis of Ag, Cu mono and bimetallic nanoparticles and their in vitro toxicity studies. / Thakore, Sonal I.; Nagar, Padamanabhi S.; Jadeja, Ravirajsinh N.; Thounaojam, Menaka; Devkar, Ranjitsinh V.; Rathore, Puran Singh.

In: Arabian Journal of Chemistry, Vol. 12, No. 5, 01.07.2019, p. 694-700.

Research output: Contribution to journalArticle

Thakore, Sonal I. ; Nagar, Padamanabhi S. ; Jadeja, Ravirajsinh N. ; Thounaojam, Menaka ; Devkar, Ranjitsinh V. ; Rathore, Puran Singh. / Sapota fruit latex mediated synthesis of Ag, Cu mono and bimetallic nanoparticles and their in vitro toxicity studies. In: Arabian Journal of Chemistry. 2019 ; Vol. 12, No. 5. pp. 694-700.
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