Spheres without influence: Dissociating invitro self-renewal from tumorigenic potential in glioma

Tracy Ann Read, Robert J. Wechsler-Reya

Research output: Contribution to journalShort surveypeer-review

6 Scopus citations

Abstract

The capacity for self-renewal is thought to be a critical property of tumor-initiating cells. This capacity is often associated with the ability to generate spheres invitro. In this issue of Cancer Cell, Barrett etal. show that cells lacking sphere-forming ability can still be very efficient at propagating tumors.

Original languageEnglish (US)
Pages (from-to)1-3
Number of pages3
JournalCancer Cell
Volume21
Issue number1
DOIs
StatePublished - Jan 17 2012
Externally publishedYes

ASJC Scopus subject areas

  • Oncology
  • Cell Biology
  • Cancer Research

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