Stability of human stromal-derived factor-1α (CXCL12α) after blood sampling

Brian Kirkpatrick; Linh Nguyen; Galina Kondrikova; Samuel Herberg; William D. Hill

Stability of human stromal-derived factor-1α (CXCL12α) after blood sampling

Brian Kirkpatrick, Linh Nguyen, Galina Kondrikova, Samuel Herberg, William D. Hill

Cellular Biology and Anatomy

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

Abstract

Stromal-derived factor 1-alpha (SDF-1α, or CXCL12α) is a major chemokine that controls adult stem cell trafficking. Little is known about its stability after blood sampling, but this is a crucial issue for clinical studies of this molecule. In a study of six subjects, we found total human plasma SDF-1α concentrations to be stable for 120 min when the blood is placed on ice immediately after sampling.

Original language	English (US)
Pages (from-to)	257-260
Number of pages	4
Journal	Annals of Clinical and Laboratory Science
Volume	40
Issue number	3
State	Published - Jun 2010

Keywords

CXCL12α
Chemokines
Stromal-derived factor-1α

ASJC Scopus subject areas

Microbiology
Immunology and Allergy
Pathology and Forensic Medicine
Immunology
Molecular Biology
Hematology
Clinical Biochemistry
Medical Laboratory Technology

Cite this

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abstract = "Stromal-derived factor 1-alpha (SDF-1α, or CXCL12α) is a major chemokine that controls adult stem cell trafficking. Little is known about its stability after blood sampling, but this is a crucial issue for clinical studies of this molecule. In a study of six subjects, we found total human plasma SDF-1α concentrations to be stable for 120 min when the blood is placed on ice immediately after sampling.",

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AU - Kirkpatrick, Brian

AU - Nguyen, Linh

AU - Kondrikova, Galina

AU - Herberg, Samuel

AU - Hill, William D.

PY - 2010/6

Y1 - 2010/6

N2 - Stromal-derived factor 1-alpha (SDF-1α, or CXCL12α) is a major chemokine that controls adult stem cell trafficking. Little is known about its stability after blood sampling, but this is a crucial issue for clinical studies of this molecule. In a study of six subjects, we found total human plasma SDF-1α concentrations to be stable for 120 min when the blood is placed on ice immediately after sampling.

AB - Stromal-derived factor 1-alpha (SDF-1α, or CXCL12α) is a major chemokine that controls adult stem cell trafficking. Little is known about its stability after blood sampling, but this is a crucial issue for clinical studies of this molecule. In a study of six subjects, we found total human plasma SDF-1α concentrations to be stable for 120 min when the blood is placed on ice immediately after sampling.

KW - CXCL12α

KW - Chemokines

KW - Stromal-derived factor-1α

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M3 - Article

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AN - SCOPUS:77955834773

SN - 0091-7370

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JO - Annals of Clinical and Laboratory Science

JF - Annals of Clinical and Laboratory Science

IS - 3

ER -

Stability of human stromal-derived factor-1α (CXCL12α) after blood sampling

Abstract

Keywords

ASJC Scopus subject areas

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