Stem cell applications for treatment of cancer and autoimmune diseases: Its promises, obstacles, and future perspectives

Yousef M. Hawsawi, Faisal Al-Zahrani, Charalampos Harris Mavromatis, Mohammed A. Baghdadi, Shalini Saggu, Atif Abdulwahab A. Oyouni

Research output: Contribution to journalReview articlepeer-review

10 Scopus citations

Abstract

Since the original discovery of stem cells, a new era of promising results has emerged in the clinical application of stem cells for the treatment of several important diseases, including cancer and autoimmune diseases. The plentiful research on stem cells during the past decades has provided significant information on the developmental, morphological, and physiological processes that govern tissue and organ formation, maintenance, and regeneration; cellular differentiation; molecular processes; and tissue homeostasis. In this review, we present the history of the use of stem cells in different clinical applications. Furthermore, we discuss the various therapeutic options for stem cells in cancer, followed by the role of stem cells in the treatment of autoimmune disorders. Additionally, we highlight the risks of and obstacles to the application of stem cells in clinical practice. Ultimately, we show future perspectives in stem cell use, with an aim to improve the clinical usefulness of stem cells.

Original languageEnglish (US)
JournalTechnology in Cancer Research and Treatment
Volume17
DOIs
StatePublished - Jan 2018
Externally publishedYes

Keywords

  • Autoimmune disease
  • Cancer
  • Clinical advances
  • Stem cells

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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