Striatal dopamine D2/D3 receptor availability in male smokers

Yen Kuang Yang, Wei Jen Yao, Joseph P. McEvoy, Ching Lin Chu, I. Hui Lee, Po See Chen, Tzung Lieh Yeh, Nan Tsing Chiu

Research output: Contribution to journalArticlepeer-review

20 Scopus citations

Abstract

It has been reported that the activation of the nicotine receptor evokes central endogenous dopamine release. However, whether smoking affects striatal dopamine D2/D3 availability over the long run has not been well established in vivo. Fifteen male smokers and their matching controls were recruited. Striatal dopamine D2/D3 receptor availability was assessed by single photon emission computed tomography with [ 123]IBZM Iodo-benzaimide. There was no significant difference in striatal D2/D3 receptor availability between smokers and controls.

Original languageEnglish (US)
Pages (from-to)87-90
Number of pages4
JournalPsychiatry Research - Neuroimaging
Volume146
Issue number1
DOIs
StatePublished - Jan 30 2006
Externally publishedYes

Keywords

  • Smokers
  • Striatal dopamine D receptor

ASJC Scopus subject areas

  • Neuroscience (miscellaneous)
  • Radiology Nuclear Medicine and imaging
  • Psychiatry and Mental health

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