Successful management of central nervous system infection due to Propionibacterium acnes with vancomycin and doxycycline

Michael E. Fincher, Mary Forsyth, Scott Y Rahimi

Research output: Contribution to journalArticle

6 Scopus citations


Propionibacterium acnes is an infrequent but increasingly recognized cause of neurosurgical infections. In this setting, it has been most commonly reported as complicating neurosurgical shunt procedures. The optimum therapy for central nervous system infections caused by P acnes has not been established. The authors report on a patient who had development of P acnes central nervous system infection after craniotomy for subdural hematoma. This case was successfully treated with prolonged therapy with vancomycin and doxycycline. Neurologic symptom improvement and radiographic resolution were documented on this regimen, and neurosurgical intervention was not required.

Original languageEnglish (US)
Pages (from-to)118-121
Number of pages4
JournalSouthern Medical Journal
Issue number1
Publication statusPublished - Jan 1 2005
Externally publishedYes



  • Craniotomy
  • Neurosurgical infections
  • Propionibacterium acnes

ASJC Scopus subject areas

  • Medicine(all)

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