Surgical management of intractable epilepsy in children with hemophilia

David John Yeh, Mark Lee, Yong D Park, Joseph R. Smith, Alton L. Lightsey

Research output: Contribution to journalArticle

1 Scopus citations


Intracranial hemorrhage occurs in 2-8% of patients with hemophilia and can result in neurologic sequelae including seizure disorders. There is a paucity of data concerning the surgical treatment of epilepsy in children with hemophilia. We review our experience with 2 children who developed medically refractory seizure disorders. Both children underwent hemispherotomy, at 18 months (case 1) and 13 years of age (case 2), respectively. Perioperative management included continuous factor replacement. Both children tolerated surgical intervention without complications or increased neurologic deficit. Case 2 showed a 90% reduction in seizure frequency, and case 1 is seizure free. Surgical management of intractable epilepsy in children with hemophilia is safe and effective. Copyright (C) 2000 S. Karger AG, Basel.

Original languageEnglish (US)
Pages (from-to)88-94
Number of pages7
JournalStereotactic and Functional Neurosurgery
Issue number1-4
Publication statusPublished - Jan 1 1999



  • Epilepsy
  • Epilepsy surgery
  • Hemispherotomy
  • Hemophilia
  • Intracranial hemorrhage

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology

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