Surgical management of intractable epilepsy in children with hemophilia

David John Yeh, Mark Lee, Yong D Park, Joseph R. Smith, Alton L. Lightsey

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Intracranial hemorrhage occurs in 2-8% of patients with hemophilia and can result in neurologic sequelae including seizure disorders. There is a paucity of data concerning the surgical treatment of epilepsy in children with hemophilia. We review our experience with 2 children who developed medically refractory seizure disorders. Both children underwent hemispherotomy, at 18 months (case 1) and 13 years of age (case 2), respectively. Perioperative management included continuous factor replacement. Both children tolerated surgical intervention without complications or increased neurologic deficit. Case 2 showed a 90% reduction in seizure frequency, and case 1 is seizure free. Surgical management of intractable epilepsy in children with hemophilia is safe and effective. Copyright (C) 2000 S. Karger AG, Basel.

Original languageEnglish (US)
Pages (from-to)88-94
Number of pages7
JournalStereotactic and Functional Neurosurgery
Volume73
Issue number1-4
DOIs
StatePublished - Jan 1 1999

Fingerprint

Hemophilia A
Epilepsy
Seizures
Intracranial Hemorrhages
Neurologic Manifestations
Nervous System
Drug Resistant Epilepsy

Keywords

  • Epilepsy
  • Epilepsy surgery
  • Hemispherotomy
  • Hemophilia
  • Intracranial hemorrhage

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology

Cite this

Surgical management of intractable epilepsy in children with hemophilia. / Yeh, David John; Lee, Mark; Park, Yong D; Smith, Joseph R.; Lightsey, Alton L.

In: Stereotactic and Functional Neurosurgery, Vol. 73, No. 1-4, 01.01.1999, p. 88-94.

Research output: Contribution to journalArticle

Yeh, David John ; Lee, Mark ; Park, Yong D ; Smith, Joseph R. ; Lightsey, Alton L. / Surgical management of intractable epilepsy in children with hemophilia. In: Stereotactic and Functional Neurosurgery. 1999 ; Vol. 73, No. 1-4. pp. 88-94.
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