@article{8e02b30db5f94670a6f30a780b8a4b46,
title = "Susceptibility to type I diabetes: HLA-DQ and DR revisited",
abstract = "The HLA class II region encodes the strongest genetic contribution to insulin-dependent diabetes mellitus (IDDM); however, the complex HLA associations with IDDM are not yet fully understood. Here, Jin-Xiong She argues that all DR and DQ molecules in an individual act in concert to determine the overall HLA-encoded susceptibility to IDDM and that apparent inter-racial discrepancies of HLA associations can be explained by DR-DQ linkage disequilibrium or by DQ αβ trans-complementation.",
author = "She, {Jin Xiong}",
note = "Funding Information: This work was supported by the Juvenile Diabetes Foundation (grants JDF193182 and JDF195094)a nd the National Institutes of Health (grant HL47138). I thank V. Ramiya, A. Muir, N.K. Maclaren, M. Yui, B. Winter, G. Thomson,J . C.urnelius,H .S. Huang and D. Schatz for their valuables ug-gestionso n the manuscripta nd/or for providing patients amples.I am alho grateful to a11m y students and technicala ssistants,p articularly J.T. Peng, J.Y. She, L.P. Zhang, D.F. Luo and M.M. Bui. Copyright: Copyright 2018 Elsevier B.V., All rights reserved.",
year = "1996",
month = jul,
doi = "10.1016/0167-5699(96)10014-1",
language = "English (US)",
volume = "17",
pages = "323--329",
journal = "Trends in Immunology",
issn = "1471-4906",
publisher = "Elsevier Limited",
number = "7",
}