T-cell epitope peptide vaccines

Sherine F. Elsawa, David A. Rodeberg, Esteban Celis

Research output: Contribution to journalReview articlepeer-review

22 Scopus citations

Abstract

T-cell immunotherapy is a promising treatment option for cancer. The identification of tumor antigens that are recognized by the immune system has allowed for the generation of vaccines for various malignancies. Due to the ease of manufacturing and characterizating peptide-based vaccines they have been used to stimulate antitumor T-cells. This article will review the use of peptide-based vaccines for the treatment of cancer by inducing antitumor T-lymphocyte responses.

Original languageEnglish (US)
Pages (from-to)563-575
Number of pages13
JournalExpert Review of Vaccines
Volume3
Issue number5
DOIs
StatePublished - Oct 1 2004
Externally publishedYes

Keywords

  • Cancer
  • Peptide vaccines
  • T-cell epitopes

ASJC Scopus subject areas

  • Immunology
  • Molecular Medicine
  • Pharmacology
  • Drug Discovery

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