The effect of a regional hepatopancreaticobiliary surgical program on clinical volume, quality of cancer care, and outcomes in the veterans affairs system

Kelsey S. Lau, Aitua Salami, Gala M. Barden, Shumaila Khawja, Diana L. Castillo, Victoria Poppelaars, Avo Artinyan, Samir S. Awad, David H. Berger, Daniel Albo, Daniel A. Anaya

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

IMPORTANCE: Malignant neoplasms of the hepatopancreaticobiliary (HPB) system constitute a significant public health problem worldwide. Treatment coordination for these tumors is challenging and can result in substandard care. Referral centers for HPB disease have been used as a strategy to improve postoperative outcomes, but their effect on accomplishing regionalization of care and improving quality of cancer care is not well known. OBJECTIVE: To evaluate the effect of implementing a multidisciplinary HPB surgical program (HPB-SP) on regionalization of care, the quality of cancer care, and surgical outcomes within an integrated health care system. DESIGN, SETTING, AND PARTICIPANTS: We designed a retrospective cohort study in a tertiary referral Veterans Affairs (VA) medical center within an 8-state designated VA health care region from November 23, 2005, through December 31, 2013.We compared patients with HPB tumors undergoing evaluation by the surgical oncology service before and after implementation of the HPB-SP on November 1, 2008. EXPOSURES: Implementation of the HPB-SP to improve access to specialized, multidisciplinary cancer care for veterans across the region. MAIN OUTCOMES AND MEASURES: Clinical and surgical volume, proportion of patients undergoing a comprehensive multidisciplinary evaluation, and postoperative adverse events included as a composite outcome defined by occurrence of postoperative mortality, severe complications, and/or reoperation. RESULTS: We identified 516 patients referred to the surgical oncology service. Establishment of the HPB-SP resulted in significant increases in regional referrals (17.3%vs 44.4%; P < .001), median monthly clinic visits (5 vs 20; P < .001), and median number of HPB surgical procedures (3 vs 9; P = .003) per quarter. Multidisciplinary assessment increased from 52.6% to 70.0%(P < .001). When we compared patients with hepatocellular carcinoma before (n = 55) and after (n = 131) implementation, more patients received any treatment (35 [63.6%] vs 109 [83.2%]; P = .004) with increased use of liver resection (0 vs 20 [15.3%]; P = .002), percutaneous ablation (0 vs 15 [11.5%]; P = .009), and oncosurgical strategies (0 vs 16 [12.2%]; P = .007) after implementation. Among patients with colorectal liver metastases (29 before vs 76 after implementation), a significant shift occurred from use of ablations (5 [17.2%] vs 3 [3.9]%; P = .02) to resections (6 [20.7%] vs 40 [52.6%]; P = .003), and use of perioperative chemotherapy increased (5 of 11 [45.5%] vs 33 of 43 [76.7%]; P = .01). The HPB-SP was associated with lower odds of postoperative adverse events, even after adjusting for important covariates (odds ratio, 0.29 [95%CI, 0.12-0.68]; P = .005), and a high rate of margin-negative liver (94.6%) and pancreatic (90.0%) resections. CONCLUSIONS AND RELEVANCE: The development of an HPB-SP led to regionalization of care and improved quality of cancer care and surgical outcomes. Establishment of regional programs within the VA system can help improve the quality of care for patients presenting with complex cancers requiring subspecialized care.

Original languageEnglish (US)
Pages (from-to)1153-1161
Number of pages9
JournalJAMA Surgery
Volume149
Issue number11
DOIs
StatePublished - Nov 1 2014

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Quality of Health Care
Veterans
Neoplasms
Referral and Consultation
Liver
Integrated Delivery of Health Care
Veterans Health
Ambulatory Care
Reoperation
Hepatocellular Carcinoma
Cohort Studies
Retrospective Studies
Public Health
Odds Ratio
Neoplasm Metastasis
Delivery of Health Care
Drug Therapy
Mortality
Therapeutics

ASJC Scopus subject areas

  • Surgery
  • Medicine(all)

Cite this

The effect of a regional hepatopancreaticobiliary surgical program on clinical volume, quality of cancer care, and outcomes in the veterans affairs system. / Lau, Kelsey S.; Salami, Aitua; Barden, Gala M.; Khawja, Shumaila; Castillo, Diana L.; Poppelaars, Victoria; Artinyan, Avo; Awad, Samir S.; Berger, David H.; Albo, Daniel; Anaya, Daniel A.

In: JAMA Surgery, Vol. 149, No. 11, 01.11.2014, p. 1153-1161.

Research output: Contribution to journalArticle

Lau, KS, Salami, A, Barden, GM, Khawja, S, Castillo, DL, Poppelaars, V, Artinyan, A, Awad, SS, Berger, DH, Albo, D & Anaya, DA 2014, 'The effect of a regional hepatopancreaticobiliary surgical program on clinical volume, quality of cancer care, and outcomes in the veterans affairs system', JAMA Surgery, vol. 149, no. 11, pp. 1153-1161. https://doi.org/10.1001/jamasurg.2014.1711
Lau, Kelsey S. ; Salami, Aitua ; Barden, Gala M. ; Khawja, Shumaila ; Castillo, Diana L. ; Poppelaars, Victoria ; Artinyan, Avo ; Awad, Samir S. ; Berger, David H. ; Albo, Daniel ; Anaya, Daniel A. / The effect of a regional hepatopancreaticobiliary surgical program on clinical volume, quality of cancer care, and outcomes in the veterans affairs system. In: JAMA Surgery. 2014 ; Vol. 149, No. 11. pp. 1153-1161.
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abstract = "IMPORTANCE: Malignant neoplasms of the hepatopancreaticobiliary (HPB) system constitute a significant public health problem worldwide. Treatment coordination for these tumors is challenging and can result in substandard care. Referral centers for HPB disease have been used as a strategy to improve postoperative outcomes, but their effect on accomplishing regionalization of care and improving quality of cancer care is not well known. OBJECTIVE: To evaluate the effect of implementing a multidisciplinary HPB surgical program (HPB-SP) on regionalization of care, the quality of cancer care, and surgical outcomes within an integrated health care system. DESIGN, SETTING, AND PARTICIPANTS: We designed a retrospective cohort study in a tertiary referral Veterans Affairs (VA) medical center within an 8-state designated VA health care region from November 23, 2005, through December 31, 2013.We compared patients with HPB tumors undergoing evaluation by the surgical oncology service before and after implementation of the HPB-SP on November 1, 2008. EXPOSURES: Implementation of the HPB-SP to improve access to specialized, multidisciplinary cancer care for veterans across the region. MAIN OUTCOMES AND MEASURES: Clinical and surgical volume, proportion of patients undergoing a comprehensive multidisciplinary evaluation, and postoperative adverse events included as a composite outcome defined by occurrence of postoperative mortality, severe complications, and/or reoperation. RESULTS: We identified 516 patients referred to the surgical oncology service. Establishment of the HPB-SP resulted in significant increases in regional referrals (17.3{\%}vs 44.4{\%}; P < .001), median monthly clinic visits (5 vs 20; P < .001), and median number of HPB surgical procedures (3 vs 9; P = .003) per quarter. Multidisciplinary assessment increased from 52.6{\%} to 70.0{\%}(P < .001). When we compared patients with hepatocellular carcinoma before (n = 55) and after (n = 131) implementation, more patients received any treatment (35 [63.6{\%}] vs 109 [83.2{\%}]; P = .004) with increased use of liver resection (0 vs 20 [15.3{\%}]; P = .002), percutaneous ablation (0 vs 15 [11.5{\%}]; P = .009), and oncosurgical strategies (0 vs 16 [12.2{\%}]; P = .007) after implementation. Among patients with colorectal liver metastases (29 before vs 76 after implementation), a significant shift occurred from use of ablations (5 [17.2{\%}] vs 3 [3.9]{\%}; P = .02) to resections (6 [20.7{\%}] vs 40 [52.6{\%}]; P = .003), and use of perioperative chemotherapy increased (5 of 11 [45.5{\%}] vs 33 of 43 [76.7{\%}]; P = .01). The HPB-SP was associated with lower odds of postoperative adverse events, even after adjusting for important covariates (odds ratio, 0.29 [95{\%}CI, 0.12-0.68]; P = .005), and a high rate of margin-negative liver (94.6{\%}) and pancreatic (90.0{\%}) resections. CONCLUSIONS AND RELEVANCE: The development of an HPB-SP led to regionalization of care and improved quality of cancer care and surgical outcomes. Establishment of regional programs within the VA system can help improve the quality of care for patients presenting with complex cancers requiring subspecialized care.",
author = "Lau, {Kelsey S.} and Aitua Salami and Barden, {Gala M.} and Shumaila Khawja and Castillo, {Diana L.} and Victoria Poppelaars and Avo Artinyan and Awad, {Samir S.} and Berger, {David H.} and Daniel Albo and Anaya, {Daniel A.}",
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T1 - The effect of a regional hepatopancreaticobiliary surgical program on clinical volume, quality of cancer care, and outcomes in the veterans affairs system

AU - Lau, Kelsey S.

AU - Salami, Aitua

AU - Barden, Gala M.

AU - Khawja, Shumaila

AU - Castillo, Diana L.

AU - Poppelaars, Victoria

AU - Artinyan, Avo

AU - Awad, Samir S.

AU - Berger, David H.

AU - Albo, Daniel

AU - Anaya, Daniel A.

PY - 2014/11/1

Y1 - 2014/11/1

N2 - IMPORTANCE: Malignant neoplasms of the hepatopancreaticobiliary (HPB) system constitute a significant public health problem worldwide. Treatment coordination for these tumors is challenging and can result in substandard care. Referral centers for HPB disease have been used as a strategy to improve postoperative outcomes, but their effect on accomplishing regionalization of care and improving quality of cancer care is not well known. OBJECTIVE: To evaluate the effect of implementing a multidisciplinary HPB surgical program (HPB-SP) on regionalization of care, the quality of cancer care, and surgical outcomes within an integrated health care system. DESIGN, SETTING, AND PARTICIPANTS: We designed a retrospective cohort study in a tertiary referral Veterans Affairs (VA) medical center within an 8-state designated VA health care region from November 23, 2005, through December 31, 2013.We compared patients with HPB tumors undergoing evaluation by the surgical oncology service before and after implementation of the HPB-SP on November 1, 2008. EXPOSURES: Implementation of the HPB-SP to improve access to specialized, multidisciplinary cancer care for veterans across the region. MAIN OUTCOMES AND MEASURES: Clinical and surgical volume, proportion of patients undergoing a comprehensive multidisciplinary evaluation, and postoperative adverse events included as a composite outcome defined by occurrence of postoperative mortality, severe complications, and/or reoperation. RESULTS: We identified 516 patients referred to the surgical oncology service. Establishment of the HPB-SP resulted in significant increases in regional referrals (17.3%vs 44.4%; P < .001), median monthly clinic visits (5 vs 20; P < .001), and median number of HPB surgical procedures (3 vs 9; P = .003) per quarter. Multidisciplinary assessment increased from 52.6% to 70.0%(P < .001). When we compared patients with hepatocellular carcinoma before (n = 55) and after (n = 131) implementation, more patients received any treatment (35 [63.6%] vs 109 [83.2%]; P = .004) with increased use of liver resection (0 vs 20 [15.3%]; P = .002), percutaneous ablation (0 vs 15 [11.5%]; P = .009), and oncosurgical strategies (0 vs 16 [12.2%]; P = .007) after implementation. Among patients with colorectal liver metastases (29 before vs 76 after implementation), a significant shift occurred from use of ablations (5 [17.2%] vs 3 [3.9]%; P = .02) to resections (6 [20.7%] vs 40 [52.6%]; P = .003), and use of perioperative chemotherapy increased (5 of 11 [45.5%] vs 33 of 43 [76.7%]; P = .01). The HPB-SP was associated with lower odds of postoperative adverse events, even after adjusting for important covariates (odds ratio, 0.29 [95%CI, 0.12-0.68]; P = .005), and a high rate of margin-negative liver (94.6%) and pancreatic (90.0%) resections. CONCLUSIONS AND RELEVANCE: The development of an HPB-SP led to regionalization of care and improved quality of cancer care and surgical outcomes. Establishment of regional programs within the VA system can help improve the quality of care for patients presenting with complex cancers requiring subspecialized care.

AB - IMPORTANCE: Malignant neoplasms of the hepatopancreaticobiliary (HPB) system constitute a significant public health problem worldwide. Treatment coordination for these tumors is challenging and can result in substandard care. Referral centers for HPB disease have been used as a strategy to improve postoperative outcomes, but their effect on accomplishing regionalization of care and improving quality of cancer care is not well known. OBJECTIVE: To evaluate the effect of implementing a multidisciplinary HPB surgical program (HPB-SP) on regionalization of care, the quality of cancer care, and surgical outcomes within an integrated health care system. DESIGN, SETTING, AND PARTICIPANTS: We designed a retrospective cohort study in a tertiary referral Veterans Affairs (VA) medical center within an 8-state designated VA health care region from November 23, 2005, through December 31, 2013.We compared patients with HPB tumors undergoing evaluation by the surgical oncology service before and after implementation of the HPB-SP on November 1, 2008. EXPOSURES: Implementation of the HPB-SP to improve access to specialized, multidisciplinary cancer care for veterans across the region. MAIN OUTCOMES AND MEASURES: Clinical and surgical volume, proportion of patients undergoing a comprehensive multidisciplinary evaluation, and postoperative adverse events included as a composite outcome defined by occurrence of postoperative mortality, severe complications, and/or reoperation. RESULTS: We identified 516 patients referred to the surgical oncology service. Establishment of the HPB-SP resulted in significant increases in regional referrals (17.3%vs 44.4%; P < .001), median monthly clinic visits (5 vs 20; P < .001), and median number of HPB surgical procedures (3 vs 9; P = .003) per quarter. Multidisciplinary assessment increased from 52.6% to 70.0%(P < .001). When we compared patients with hepatocellular carcinoma before (n = 55) and after (n = 131) implementation, more patients received any treatment (35 [63.6%] vs 109 [83.2%]; P = .004) with increased use of liver resection (0 vs 20 [15.3%]; P = .002), percutaneous ablation (0 vs 15 [11.5%]; P = .009), and oncosurgical strategies (0 vs 16 [12.2%]; P = .007) after implementation. Among patients with colorectal liver metastases (29 before vs 76 after implementation), a significant shift occurred from use of ablations (5 [17.2%] vs 3 [3.9]%; P = .02) to resections (6 [20.7%] vs 40 [52.6%]; P = .003), and use of perioperative chemotherapy increased (5 of 11 [45.5%] vs 33 of 43 [76.7%]; P = .01). The HPB-SP was associated with lower odds of postoperative adverse events, even after adjusting for important covariates (odds ratio, 0.29 [95%CI, 0.12-0.68]; P = .005), and a high rate of margin-negative liver (94.6%) and pancreatic (90.0%) resections. CONCLUSIONS AND RELEVANCE: The development of an HPB-SP led to regionalization of care and improved quality of cancer care and surgical outcomes. Establishment of regional programs within the VA system can help improve the quality of care for patients presenting with complex cancers requiring subspecialized care.

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