Recognition of the many 'faces' of Graves' disease can lead to earlier detection and management. Diagnosis is not always obvious, and this common multisystem syndrome requires attentive clinical evaluation. New laboratory and nuclear medicine diagnostic procedures now allow precise biochemical and pathophysiologic confirmation of the disease. Beta blockers promptly alleviate symptoms, allowing time for thoughtful consideration by patient and physician as to optimal definitive therapy with antithyroid drugs, RAI, or surgery.
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