The monoclonal antibody A2B5 is specific to ganglioside GQ1c

Noriyuki Kasai, Robert K. Yu

Research output: Contribution to journalArticle

90 Scopus citations

Abstract

The neural specific monoclonal antibody A2B5 was found to interact with GQ1c but not with GQ1b, nor did it interact with other glycolipids such as GM1, GD1a, GD1b, GT1a, GT1b and GA1. Since GQ1c is enriched in embryonic chicken brains but not in adult chicken brains, this antibody should be useful as a tool in assessing the role of GQ1c in neuronal maturation.

Original languageEnglish (US)
Pages (from-to)155-158
Number of pages4
JournalBrain Research
Volume277
Issue number1
DOIs
StatePublished - Oct 24 1983
Externally publishedYes

Keywords

  • gangliosides
  • monoclonal antibody A2B5
  • neuronal maturation
  • tetrasialoganglosides

ASJC Scopus subject areas

  • Neuroscience(all)
  • Molecular Biology
  • Clinical Neurology
  • Developmental Biology

Fingerprint Dive into the research topics of 'The monoclonal antibody A2B5 is specific to ganglioside G<sub>Q1c</sub>'. Together they form a unique fingerprint.

  • Cite this