The role of gadolinium-DTPA-enhanced magnetic resonance imaging in presurgical evaluation for intractable partial epilepsy

James W. Wheless, R. E. Figueroa-Ortiz, E. F. Binet, D. W. King, B. B. Gallagher, A. M. Murro, H. F. Flanigin, J. R. Smith, M. M. Leveridge

Research output: Contribution to journalArticle

1 Scopus citations

Abstract

In order to evaluate the diagnostic efficacy of gadolinium-DTPA (Gd-DTPA), we performed enhanced and unenhanced magnetic resonance imaging (MRI) of the head in 48 Phase I presurgical patients. Fifty-two percent had normal MRI (unenhanced and enhanced). Forty-eight percent had abnormal unenhanced MRI. Gd-DTPA MRI was helpful preoperatively in 57% of these patients. Gd-DTPA improves the diagnostic sensitivity of MRI and provides important additional information in the presurgical evaluation of patients with partial epilepsy only if the unenhanced MRI is abnormal.

Original languageEnglish (US)
Pages (from-to)95-101
Number of pages7
JournalJournal of Epilepsy
Volume4
Issue number2
DOIs
StatePublished - 1991

Keywords

  • Epilepsy surgery
  • Gadolinium-DTPA
  • Intractable partial seizures
  • Magnetic resonance imaging

ASJC Scopus subject areas

  • Neuroscience(all)
  • Clinical Neurology

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