Abstract
Although there are many compounds that may be beneficial for the treatment of various neurological injuries (ischemic or traumatic) there is but one, Mg2+, that has had a rich and controversial history. The physiological investigation of the role of Mg2+ in medicine has had a long history. However, it might come as a surprise that the history of the role of Mg2+ in the pathophysiology of neurological injuries is well over two decades old. The focus of this chapter is to review the available literature on the effects of Mg2 + on the pathophysiology and behavioral recovery from neurological injuries. In addition, data from our laboratory will be presented that has investigated the effects of Mg2 + therapy on recovery of function in the traumatically injured brain.
| Original language | English (US) |
|---|---|
| Title of host publication | Metal Ion in Stroke |
| Publisher | Springer New York |
| Pages | 431-444 |
| Number of pages | 14 |
| ISBN (Electronic) | 9781441996633 |
| ISBN (Print) | 9781441996626 |
| DOIs | |
| State | Published - Jan 1 2012 |
| Externally published | Yes |
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Keywords
- Behavior
- Rat
- Recovery of function
- Stroke
- Traumatic brain injury
ASJC Scopus subject areas
- Medicine(all)
- Neuroscience(all)
Cite this
The role of magnesium in the pathophysiology and treatment of stroke and other neurological injuries. / Hoane, Michael R.
Metal Ion in Stroke. Springer New York, 2012. p. 431-444.Research output: Chapter in Book/Report/Conference proceeding › Chapter
}
TY - CHAP
T1 - The role of magnesium in the pathophysiology and treatment of stroke and other neurological injuries
AU - Hoane, Michael R.
PY - 2012/1/1
Y1 - 2012/1/1
N2 - Although there are many compounds that may be beneficial for the treatment of various neurological injuries (ischemic or traumatic) there is but one, Mg2+, that has had a rich and controversial history. The physiological investigation of the role of Mg2+ in medicine has had a long history. However, it might come as a surprise that the history of the role of Mg2+ in the pathophysiology of neurological injuries is well over two decades old. The focus of this chapter is to review the available literature on the effects of Mg2 + on the pathophysiology and behavioral recovery from neurological injuries. In addition, data from our laboratory will be presented that has investigated the effects of Mg2 + therapy on recovery of function in the traumatically injured brain.
AB - Although there are many compounds that may be beneficial for the treatment of various neurological injuries (ischemic or traumatic) there is but one, Mg2+, that has had a rich and controversial history. The physiological investigation of the role of Mg2+ in medicine has had a long history. However, it might come as a surprise that the history of the role of Mg2+ in the pathophysiology of neurological injuries is well over two decades old. The focus of this chapter is to review the available literature on the effects of Mg2 + on the pathophysiology and behavioral recovery from neurological injuries. In addition, data from our laboratory will be presented that has investigated the effects of Mg2 + therapy on recovery of function in the traumatically injured brain.
KW - Behavior
KW - Rat
KW - Recovery of function
KW - Stroke
KW - Traumatic brain injury
UR - http://www.scopus.com/inward/record.url?scp=85027307869&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85027307869&partnerID=8YFLogxK
U2 - 10.1007/978-1-4419-9663-3_21
DO - 10.1007/978-1-4419-9663-3_21
M3 - Chapter
SN - 9781441996626
SP - 431
EP - 444
BT - Metal Ion in Stroke
PB - Springer New York
ER -