The role of magnesium in the pathophysiology and treatment of stroke and other neurological injuries

Michael R. Hoane

doi:10.1007/978-1-4419-9663-3_21

The role of magnesium in the pathophysiology and treatment of stroke and other neurological injuries

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Although there are many compounds that may be beneficial for the treatment of various neurological injuries (ischemic or traumatic) there is but one, Mg²⁺, that has had a rich and controversial history. The physiological investigation of the role of Mg²+ in medicine has had a long history. However, it might come as a surprise that the history of the role of Mg²+ in the pathophysiology of neurological injuries is well over two decades old. The focus of this chapter is to review the available literature on the effects of Mg^{2 +} on the pathophysiology and behavioral recovery from neurological injuries. In addition, data from our laboratory will be presented that has investigated the effects of Mg^{2 +} therapy on recovery of function in the traumatically injured brain.

Original language	English (US)
Title of host publication	Metal Ion in Stroke
Publisher	Springer New York
Pages	431-444
Number of pages	14
ISBN (Electronic)	9781441996633
ISBN (Print)	9781441996626
DOIs	https://doi.org/10.1007/978-1-4419-9663-3_21
State	Published - Jan 1 2012
Externally published	Yes

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Keywords

Behavior
Rat
Recovery of function
Stroke
Traumatic brain injury

ASJC Scopus subject areas

Medicine(all)
Neuroscience(all)

Cite this

Hoane, M. R. (2012). The role of magnesium in the pathophysiology and treatment of stroke and other neurological injuries. In Metal Ion in Stroke (pp. 431-444). Springer New York. https://doi.org/10.1007/978-1-4419-9663-3_21

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Access to Document

10.1007/978-1-4419-9663-3_21