The role of magnesium in the pathophysiology and treatment of stroke and other neurological injuries

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Although there are many compounds that may be beneficial for the treatment of various neurological injuries (ischemic or traumatic) there is but one, Mg2+, that has had a rich and controversial history. The physiological investigation of the role of Mg2+ in medicine has had a long history. However, it might come as a surprise that the history of the role of Mg2+ in the pathophysiology of neurological injuries is well over two decades old. The focus of this chapter is to review the available literature on the effects of Mg2 + on the pathophysiology and behavioral recovery from neurological injuries. In addition, data from our laboratory will be presented that has investigated the effects of Mg2 + therapy on recovery of function in the traumatically injured brain.

Original languageEnglish (US)
Title of host publicationMetal Ion in Stroke
PublisherSpringer New York
Pages431-444
Number of pages14
ISBN (Electronic)9781441996633
ISBN (Print)9781441996626
DOIs
StatePublished - Jan 1 2012
Externally publishedYes

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Keywords

  • Behavior
  • Rat
  • Recovery of function
  • Stroke
  • Traumatic brain injury

ASJC Scopus subject areas

  • Medicine(all)
  • Neuroscience(all)

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