The Selective Inactivation of an ESF-Generating Factor (EGF) in the Presence of Erythropoietin (ESF)

Jasper P. Lewis, Emily T. Welch, W. Aubrey Neal, Russell R. Moores, William G. Lewis, Claude Starr Wright, Linda L. Smith, Coit M. Dubose

Research output: Contribution to journalArticle

8 Scopus citations

Abstract

An ESF-generating factor (EGF), erythropoietin (ESF) and a mixture of both were incubated with dithiothreitol (DTT, a protective reagent for sulfhydryl groups). Ten μM DTT completely prevented the production of 0.26 ± 0.01 IU of ESF by EGF but did not inactivate ESF. DTT was used to indicate the relative amounts of EGF and ESF activity in a mixture of both.

Original languageEnglish (US)
Pages (from-to)783-785
Number of pages3
JournalProceedings of the Society for Experimental Biology and Medicine
Volume137
Issue number3
DOIs
StatePublished - Jul 1971

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

Fingerprint Dive into the research topics of 'The Selective Inactivation of an ESF-Generating Factor (EGF) in the Presence of Erythropoietin (ESF)'. Together they form a unique fingerprint.

  • Cite this

    Lewis, J. P., Welch, E. T., Neal, W. A., Moores, R. R., Lewis, W. G., Wright, C. S., Smith, L. L., & Dubose, C. M. (1971). The Selective Inactivation of an ESF-Generating Factor (EGF) in the Presence of Erythropoietin (ESF). Proceedings of the Society for Experimental Biology and Medicine, 137(3), 783-785. https://doi.org/10.3181/00379727-137-35666