The Selective Inactivation of an ESF-Generating Factor (EGF) in the Presence of Erythropoietin (ESF)

Jasper P. Lewis, Emily T. Welch, W. Aubrey Neal, Russell R Moores, William G. Lewis, Claude Starr Wright, Linda L. Smith, Coit M. Dubose

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

An ESF-generating factor (EGF), erythropoietin (ESF) and a mixture of both were incubated with dithiothreitol (DTT, a protective reagent for sulfhydryl groups). Ten μM DTT completely prevented the production of 0.26 ± 0.01 IU of ESF by EGF but did not inactivate ESF. DTT was used to indicate the relative amounts of EGF and ESF activity in a mixture of both.

Original languageEnglish (US)
Pages (from-to)783-785
Number of pages3
JournalProceedings of the Society for Experimental Biology and Medicine
Volume137
Issue number3
DOIs
StatePublished - Jan 1 1971

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Sulfhydryl Reagents
Dithiothreitol
Erythropoietin
erythrogenin

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

The Selective Inactivation of an ESF-Generating Factor (EGF) in the Presence of Erythropoietin (ESF). / Lewis, Jasper P.; Welch, Emily T.; Neal, W. Aubrey; Moores, Russell R; Lewis, William G.; Wright, Claude Starr; Smith, Linda L.; Dubose, Coit M.

In: Proceedings of the Society for Experimental Biology and Medicine, Vol. 137, No. 3, 01.01.1971, p. 783-785.

Research output: Contribution to journalArticle

Lewis, Jasper P. ; Welch, Emily T. ; Neal, W. Aubrey ; Moores, Russell R ; Lewis, William G. ; Wright, Claude Starr ; Smith, Linda L. ; Dubose, Coit M. / The Selective Inactivation of an ESF-Generating Factor (EGF) in the Presence of Erythropoietin (ESF). In: Proceedings of the Society for Experimental Biology and Medicine. 1971 ; Vol. 137, No. 3. pp. 783-785.
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