The Selective Inactivation of an ESF-Generating Factor (EGF) in the Presence of Erythropoietin (ESF)

Jasper P. Lewis, Emily T. Welch, W. Aubrey Neal, Russell R. Moores, William G. Lewis, Claude Starr Wright, Linda L. Smith, Coit M. Dubose

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

An ESF-generating factor (EGF), erythropoietin (ESF) and a mixture of both were incubated with dithiothreitol (DTT, a protective reagent for sulfhydryl groups). Ten μM DTT completely prevented the production of 0.26 ± 0.01 IU of ESF by EGF but did not inactivate ESF. DTT was used to indicate the relative amounts of EGF and ESF activity in a mixture of both.

Original languageEnglish (US)
Pages (from-to)783-785
Number of pages3
JournalProceedings of the Society for Experimental Biology and Medicine
Volume137
Issue number3
DOIs
StatePublished - Jul 1971

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Sulfhydryl Reagents
Dithiothreitol
Erythropoietin
erythrogenin

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

The Selective Inactivation of an ESF-Generating Factor (EGF) in the Presence of Erythropoietin (ESF). / Lewis, Jasper P.; Welch, Emily T.; Neal, W. Aubrey; Moores, Russell R.; Lewis, William G.; Wright, Claude Starr; Smith, Linda L.; Dubose, Coit M.

In: Proceedings of the Society for Experimental Biology and Medicine, Vol. 137, No. 3, 07.1971, p. 783-785.

Research output: Contribution to journalArticle

Lewis, Jasper P. ; Welch, Emily T. ; Neal, W. Aubrey ; Moores, Russell R. ; Lewis, William G. ; Wright, Claude Starr ; Smith, Linda L. ; Dubose, Coit M. / The Selective Inactivation of an ESF-Generating Factor (EGF) in the Presence of Erythropoietin (ESF). In: Proceedings of the Society for Experimental Biology and Medicine. 1971 ; Vol. 137, No. 3. pp. 783-785.
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